5o71
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human USP25== | |
| - | + | <StructureSection load='5o71' size='340' side='right' caption='[[5o71]], [[Resolution|resolution]] 3.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5o71]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O71 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitinyl_hydrolase_1 Ubiquitinyl hydrolase 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.12 3.4.19.12] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o71 OCA], [http://pdbe.org/5o71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o71 RCSB], [http://www.ebi.ac.uk/pdbsum/5o71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o71 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UBP25_HUMAN UBP25_HUMAN]] Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains. The muscle-specific isoform (USP25m) may have a role in the regulation of muscular differentiation and function. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ubiquitinyl hydrolase 1]] | ||
| + | [[Category: Liu, B]] | ||
| + | [[Category: Reverter, D]] | ||
| + | [[Category: De-ubiquinating enzyme]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Usp family]] | ||
Revision as of 05:37, 20 June 2018
Crystal structure of human USP25
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