2jhp

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|PDB= 2jhp |SIZE=350|CAPTION= <scene name='initialview01'>2jhp</scene>, resolution 2.50&Aring;
|PDB= 2jhp |SIZE=350|CAPTION= <scene name='initialview01'>2jhp</scene>, resolution 2.50&Aring;
|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=GUN:GUANINE'>GUN</scene>
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|LIGAND= <scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
 +
|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhp OCA], [http://www.ebi.ac.uk/pdbsum/2jhp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jhp RCSB]</span>
}}
}}
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[[Category: Stuart, D I.]]
[[Category: Stuart, D I.]]
[[Category: Sutton, G.]]
[[Category: Sutton, G.]]
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[[Category: GUN]]
 
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[[Category: SAH]]
 
[[Category: core protein]]
[[Category: core protein]]
[[Category: guanylyltransferase]]
[[Category: guanylyltransferase]]
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[[Category: virion protein]]
[[Category: virion protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:42:07 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:21 2008''

Revision as of 00:58, 31 March 2008


PDB ID 2jhp

Drag the structure with the mouse to rotate
, resolution 2.50Å
Sites:
Ligands: ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE


Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.

About this Structure

2JHP is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654

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