6b4g
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM complex== | |
| - | + | <StructureSection load='6b4g' size='340' side='right' caption='[[6b4g]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6b4g]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B4G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B4G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b4g OCA], [http://pdbe.org/6b4g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b4g RCSB], [http://www.ebi.ac.uk/pdbsum/6b4g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b4g ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLE1_CHATD GLE1_CHATD]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.[UniProtKB:Q12315] [[http://www.uniprot.org/uniprot/AMO1_CHATD AMO1_CHATD]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). AMO1 is specifically important for nuclear protein and mRNA export.[UniProtKB:P49686] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cai, S W]] | ||
| + | [[Category: Correia, A R]] | ||
| + | [[Category: Hoelz, A]] | ||
| + | [[Category: Huber, F M]] | ||
| + | [[Category: Jette, C A]] | ||
| + | [[Category: Lin, D H]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Dead-box helicase]] | ||
| + | [[Category: Mrna export]] | ||
| + | [[Category: Nuclear pore complex]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 05:47, 20 June 2018
Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM complex
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