6b4h
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Saccharomyces cerevisiae Gle1 CTD-Nup42 GBM-IP6 complex== | |
| - | + | <StructureSection load='6b4h' size='340' side='right' caption='[[6b4h]], [[Resolution|resolution]] 2.17Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6b4h]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B4H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B4H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b4h OCA], [http://pdbe.org/6b4h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b4h RCSB], [http://www.ebi.ac.uk/pdbsum/6b4h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b4h ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AMO1_CHATD AMO1_CHATD]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). AMO1 is specifically important for nuclear protein and mRNA export.[UniProtKB:P49686] [[http://www.uniprot.org/uniprot/GLE1_CHATD GLE1_CHATD]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.[UniProtKB:Q12315] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cai, S W]] | ||
| + | [[Category: Correia, A R]] | ||
| + | [[Category: Hoelz, A]] | ||
| + | [[Category: Huber, F M]] | ||
| + | [[Category: Jette, C A]] | ||
| + | [[Category: Lin, D H]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Dead-box helicase]] | ||
| + | [[Category: Mrna export]] | ||
| + | [[Category: Nuclear pore complex]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 05:47, 20 June 2018
Crystal structure of Saccharomyces cerevisiae Gle1 CTD-Nup42 GBM-IP6 complex
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