6dcl
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Crystal structure of UP1 bound to pri-miRNA-18a terminal loop== |
| - | + | <StructureSection load='6dcl' size='340' side='right' caption='[[6dcl]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dcl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DCL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DCL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dcl OCA], [http://pdbe.org/6dcl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dcl RCSB], [http://www.ebi.ac.uk/pdbsum/6dcl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dcl ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kooshapur, H]] | ||
| + | [[Category: Sattler, M]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Hnrnp a1]] | ||
| + | [[Category: Rna]] | ||
| + | [[Category: Rna binding protein]] | ||
| + | [[Category: Rna binding protein-rna complex]] | ||
| + | [[Category: Rrm]] | ||
Revision as of 05:37, 27 June 2018
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
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