6cdh
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of ferrous form of the Cl-Tyr157 human cysteine dioxygenase with both uncrosslinked and crosslinked cofactor== | |
| - | + | <StructureSection load='6cdh' size='340' side='right' caption='[[6cdh]], [[Resolution|resolution]] 1.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6cdh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CDH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CDH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3CT:3-CHLORO-L-TYROSINE'>3CT</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_dioxygenase Cysteine dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.20 1.13.11.20] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cdh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cdh OCA], [http://pdbe.org/6cdh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cdh RCSB], [http://www.ebi.ac.uk/pdbsum/6cdh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cdh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CDO1_HUMAN CDO1_HUMAN]] Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cysteine dioxygenase]] | ||
[[Category: Li, J]] | [[Category: Li, J]] | ||
[[Category: Liu, A]] | [[Category: Liu, A]] | ||
[[Category: Shin, I]] | [[Category: Shin, I]] | ||
| + | [[Category: Cys-tyr cofactor]] | ||
| + | [[Category: Cysteine]] | ||
| + | [[Category: Iron]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Unnatural amino acid]] | ||
Revision as of 07:12, 4 July 2018
Crystal structure of ferrous form of the Cl-Tyr157 human cysteine dioxygenase with both uncrosslinked and crosslinked cofactor
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