6ew0
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol== | |
- | + | <StructureSection load='6ew0' size='340' side='right' caption='[[6ew0]], [[Resolution|resolution]] 3.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6ew0]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EW0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EW0 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ew0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ew0 OCA], [http://pdbe.org/6ew0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ew0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ew0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ew0 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_PIG TBB_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Sus scrofa]] | ||
+ | [[Category: Manka, S W]] | ||
+ | [[Category: Gtpase]] | ||
+ | [[Category: Microtubule]] | ||
+ | [[Category: Structural protein]] | ||
+ | [[Category: Taxol]] | ||
+ | [[Category: Tubulin]] |
Revision as of 07:19, 4 July 2018
Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol
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Categories: Sus scrofa | Manka, S W | Gtpase | Microtubule | Structural protein | Taxol | Tubulin