5xwe
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a three finger toxin from Ophiophagus hannah venom== | |
| - | + | <StructureSection load='5xwe' size='340' side='right' caption='[[5xwe]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5xwe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ophiophagus_hannah Ophiophagus hannah]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XWE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwe OCA], [http://pdbe.org/5xwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xwe RCSB], [http://www.ebi.ac.uk/pdbsum/5xwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwe ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/3S11H_OPHHA 3S11H_OPHHA]] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ophiophagus hannah]] | ||
| + | [[Category: Jobichen, C]] | ||
| + | [[Category: Kini, R M]] | ||
| + | [[Category: Roy, A]] | ||
| + | [[Category: Sivaraman, J]] | ||
| + | [[Category: Snake venom]] | ||
| + | [[Category: Three finger toxin]] | ||
| + | [[Category: Toxin]] | ||
Revision as of 05:37, 11 July 2018
Structure of a three finger toxin from Ophiophagus hannah venom
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