2j8l
From Proteopedia
(Difference between revisions)
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| - | ==FXI | + | |
| + | ==FXI Apple 4 domain loop-out conformation== | ||
<StructureSection load='2j8l' size='340' side='right' caption='[[2j8l]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''> | <StructureSection load='2j8l' size='340' side='right' caption='[[2j8l]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xx9|1xx9]], [[1xxd|1xxd]], [[1xxf|1xxf]], [[1zhm|1zhm]], [[1zhp|1zhp]], [[1zhr|1zhr]], [[1zjd|1zjd]], [[1zlr|1zlr]], [[1zmj|1zmj]], [[1zml|1zml]], [[1zmn|1zmn]], [[1zom|1zom]], [[1zpz|1zpz]], [[1zrk|1zrk]], [[1zsj|1zsj]], [[1zsk|1zsk]], [[1zsl|1zsl]], [[1ztj|1ztj]], [[1ztk|1ztk]], [[1ztl|1ztl]], [[2j8j|2j8j]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xx9|1xx9]], [[1xxd|1xxd]], [[1xxf|1xxf]], [[1zhm|1zhm]], [[1zhp|1zhp]], [[1zhr|1zhr]], [[1zjd|1zjd]], [[1zlr|1zlr]], [[1zmj|1zmj]], [[1zml|1zml]], [[1zmn|1zmn]], [[1zom|1zom]], [[1zpz|1zpz]], [[1zrk|1zrk]], [[1zsj|1zsj]], [[1zsk|1zsk]], [[1zsl|1zsl]], [[1ztj|1ztj]], [[1ztk|1ztk]], [[1ztl|1ztl]], [[2j8j|2j8j]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j8l OCA], [http://pdbe.org/2j8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j8l RCSB], [http://www.ebi.ac.uk/pdbsum/2j8l PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j8l OCA], [http://pdbe.org/2j8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j8l RCSB], [http://www.ebi.ac.uk/pdbsum/2j8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j8l ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j8/2j8l_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j8/2j8l_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j8l ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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[[Category: Samuel, D]] | [[Category: Samuel, D]] | ||
[[Category: Walsh, P N]] | [[Category: Walsh, P N]] | ||
| + | [[Category: Alternative splicing]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Fxi / blood coagulation / pan domain /apple domain / blood coagulation]] | [[Category: Fxi / blood coagulation / pan domain /apple domain / blood coagulation]] | ||
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[[Category: Heparin-binding]] | [[Category: Heparin-binding]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 06:32, 11 July 2018
FXI Apple 4 domain loop-out conformation
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Categories: Coagulation factor XIa | Homo sapiens | Bu, Z | Canutescu, A A | Cheng, H | Riley, P W | Roder, H | Samuel, D | Walsh, P N | Alternative splicing | Disease mutation | Fxi / blood coagulation / pan domain /apple domain / blood coagulation | Glycoprotein | Heparin-binding | Hydrolase | Polymorphism | Protease | Serine protease
