2j14

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==3,4,5-TRISUBSTITUTED ISOXAZOLES AS NOVEL PPARDELTA AGONISTS: PART2==
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==3,4,5-Trisubstituted Isoxazoles as Novel PPARdelta Agonists: Part2==
<StructureSection load='2j14' size='340' side='right' caption='[[2j14]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2j14' size='340' side='right' caption='[[2j14]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNI:(3-{4-[2-(2,4-DICHLORO-PHENOXY)-ETHYLCARBAMOYL]-5-PHENYL-ISOXAZOL-3-YL}-PHENYL)-ACETIC+ACID'>GNI</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNI:(3-{4-[2-(2,4-DICHLORO-PHENOXY)-ETHYLCARBAMOYL]-5-PHENYL-ISOXAZOL-3-YL}-PHENYL)-ACETIC+ACID'>GNI</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gwx|1gwx]], [[1y0s|1y0s]], [[2awh|2awh]], [[2b50|2b50]], [[2baw|2baw]], [[2gwx|2gwx]], [[3gwx|3gwx]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gwx|1gwx]], [[1y0s|1y0s]], [[2awh|2awh]], [[2b50|2b50]], [[2baw|2baw]], [[2gwx|2gwx]], [[3gwx|3gwx]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j14 OCA], [http://pdbe.org/2j14 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j14 RCSB], [http://www.ebi.ac.uk/pdbsum/2j14 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j14 OCA], [http://pdbe.org/2j14 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j14 RCSB], [http://www.ebi.ac.uk/pdbsum/2j14 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j14 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j14_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j14_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Xie, Y]]
[[Category: Xie, Y]]
[[Category: Activator]]
[[Category: Activator]]
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[[Category: Alternative splicing]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]
[[Category: Fatty acid]]
[[Category: Fatty acid]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 06:51, 11 July 2018

3,4,5-Trisubstituted Isoxazoles as Novel PPARdelta Agonists: Part2

2j14, resolution 2.80Å

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