2jeb
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | == | + | |
+ | ==Structure of a 9-subunit archaeal exosome bound to Mn ions== | ||
<StructureSection load='2jeb' size='340' side='right' caption='[[2jeb]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2jeb' size='340' side='right' caption='[[2jeb]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2jeb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2jeb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JEB FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2br2|2br2]], [[2c37|2c37]], [[2c38|2c38]], [[2c39|2c39]], [[2je6|2je6]], [[2jea|2jea]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2br2|2br2]], [[2c37|2c37]], [[2c38|2c38]], [[2c39|2c39]], [[2je6|2je6]], [[2jea|2jea]]</td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jeb OCA], [http://pdbe.org/2jeb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jeb RCSB], [http://www.ebi.ac.uk/pdbsum/2jeb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jeb OCA], [http://pdbe.org/2jeb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jeb RCSB], [http://www.ebi.ac.uk/pdbsum/2jeb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jeb ProSAT]</span></td></tr> |
</table> | </table> | ||
- | == Function == | ||
- | [[http://www.uniprot.org/uniprot/ECR1_SULSO ECR1_SULSO]] Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome (Potential). [[http://www.uniprot.org/uniprot/ECX1_SULSO ECX1_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2jeb_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2jeb_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
Line 30: | Line 29: | ||
==See Also== | ==See Also== | ||
- | *[[Exonuclease|Exonuclease]] | ||
*[[Exosome|Exosome]] | *[[Exosome|Exosome]] | ||
== References == | == References == | ||
Line 36: | Line 34: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Saccharolobus solfataricus]] |
[[Category: Conti, E]] | [[Category: Conti, E]] | ||
[[Category: Lorentzen, E]] | [[Category: Lorentzen, E]] |
Revision as of 06:58, 11 July 2018
Structure of a 9-subunit archaeal exosome bound to Mn ions
|
Categories: Saccharolobus solfataricus | Conti, E | Lorentzen, E | Archaeal | Exonuclease | Exoribonuclease | Exosome | Hydrolase | Nuclease | Phosphorolytic | Rna | Rna degradation | Rna-binding | Rnase ph | Rrp4 | Rrp41 | Rrp42