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2jbj
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==membrane-bound glutamate carboxypeptidase II (GCPII) in complex with 2-PMPA (2-phosphonoMethyl-pentanedioic acid)== | ||
<StructureSection load='2jbj' size='340' side='right' caption='[[2jbj]], [[Resolution|resolution]] 2.19Å' scene=''> | <StructureSection load='2jbj' size='340' side='right' caption='[[2jbj]], [[Resolution|resolution]] 2.19Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jbj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JBJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[2jbj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JBJ FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=G88:(2S)-2-(PHOSPHONOMETHYL)PENTANEDIOIC+ACID'>G88</scene>, <scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=G88:(2S)-2-(PHOSPHONOMETHYL)PENTANEDIOIC+ACID'>G88</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1z8l|1z8l]], [[2c6c|2c6c]], [[2c6g|2c6g]], [[2c6p|2c6p]], [[2cij|2cij]], [[2jbk|2jbk]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1z8l|1z8l]], [[2c6c|2c6c]], [[2c6g|2c6g]], [[2c6p|2c6p]], [[2cij|2cij]], [[2jbk|2jbk]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_carboxypeptidase_II Glutamate carboxypeptidase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.21 3.4.17.21] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_carboxypeptidase_II Glutamate carboxypeptidase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.21 3.4.17.21] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jbj OCA], [http://pdbe.org/2jbj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jbj RCSB], [http://www.ebi.ac.uk/pdbsum/2jbj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jbj OCA], [http://pdbe.org/2jbj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jbj RCSB], [http://www.ebi.ac.uk/pdbsum/2jbj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jbj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jb/2jbj_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jb/2jbj_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Hilgenfeld, R]] | [[Category: Hilgenfeld, R]] | ||
[[Category: Mesters, J R]] | [[Category: Mesters, J R]] | ||
| + | [[Category: Alternative splicing]] | ||
[[Category: Antigen]] | [[Category: Antigen]] | ||
[[Category: Carboxypeptidase]] | [[Category: Carboxypeptidase]] | ||
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[[Category: Neurodegenerative disease]] | [[Category: Neurodegenerative disease]] | ||
[[Category: Peptidase]] | [[Category: Peptidase]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Prostate cancer]] | [[Category: Prostate cancer]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
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[[Category: Signal-anchor]] | [[Category: Signal-anchor]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| + | [[Category: Zinc]] | ||
Revision as of 07:04, 11 July 2018
membrane-bound glutamate carboxypeptidase II (GCPII) in complex with 2-PMPA (2-phosphonoMethyl-pentanedioic acid)
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Categories: Glutamate carboxypeptidase II | Human | Henning, K | Hilgenfeld, R | Mesters, J R | Alternative splicing | Antigen | Carboxypeptidase | Dipeptidase | Glycoprotein | Hydrolase | Membrane | Metal- binding | Metal-binding | Metalloprotease | Multifunctional enzyme | Naaladase | Neurodegenerative disease | Peptidase | Polymorphism | Prostate cancer | Protease | Psma | Signal-anchor | Transmembrane | Zinc
