5qif

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m (Protected "5qif" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5qif is ON HOLD
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==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z31792168==
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<StructureSection load='5qif' size='340' side='right' caption='[[5qif]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Bradley, A.R., Talon, R., Brandao-Neto, J., Douangamath, A., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Brennan, P.E., Yue, W.W.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qif]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIF FirstGlance]. <br>
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Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of HAO1 in complex with Z31792168
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GWS:2-cyclohexyl-~{N}-pyridin-3-yl-ethanamide'>GWS</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>
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[[Category: Mackinnon, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qif OCA], [http://pdbe.org/5qif PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qif RCSB], [http://www.ebi.ac.uk/pdbsum/5qif PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qif ProSAT]</span></td></tr>
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[[Category: Bradley, A.R]]
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</table>
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[[Category: Arrowsmith, C.H]]
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== Function ==
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[[http://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN]] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
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__TOC__
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</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Bezerra, G A]]
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[[Category: Bountra, C]]
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[[Category: Bradley, A R]]
[[Category: Brandao-Neto, J]]
[[Category: Brandao-Neto, J]]
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[[Category: Talon, R]]
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[[Category: Brennan, P E]]
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[[Category: Brennan, P.E]]
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[[Category: Delft, F von]]
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[[Category: Oppermann, U]]
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[[Category: Douangamath, A]]
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[[Category: Bezerra, G.A]]
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[[Category: Edwards, A]]
[[Category: Edwards, A]]
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[[Category: Douangamath, A]]
 
[[Category: Krojer, T]]
[[Category: Krojer, T]]
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[[Category: Yue, W.W]]
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[[Category: MacKinnon, S]]
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[[Category: Von Delft, F]]
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[[Category: Oppermann, U]]
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[[Category: Bountra, C]]
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[[Category: Talon, R]]
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[[Category: Yue, W W]]
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[[Category: Hao1]]
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[[Category: Oxidoreductase]]
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[[Category: Pandda]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Xchemexplorer]]

Revision as of 07:21, 18 July 2018

PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z31792168

5qif, resolution 1.20Å

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