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6gpl

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m (Protected "6gpl" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6gpl is ON HOLD
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==Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man==
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<StructureSection load='6gpl' size='340' side='right' caption='[[6gpl]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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Authors: Pfeiffer, M., Krojer, T., Johansson, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Nidetzky, B., Oppermann, U., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6gpl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GPL FirstGlance]. <br>
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Description: Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F7E:[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{R},3~{S},4~{R},6~{R})-6-methyl-3,4-bis(oxidanyl)-5-oxidanylidene-oxan-2-yl]+hydrogen+phosphate'>F7E</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GDP-mannose_4,6-dehydratase GDP-mannose 4,6-dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.47 4.2.1.47] </span></td></tr>
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[[Category: Pfeiffer, M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gpl OCA], [http://pdbe.org/6gpl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gpl RCSB], [http://www.ebi.ac.uk/pdbsum/6gpl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gpl ProSAT]</span></td></tr>
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[[Category: Arrowsmith, C.H]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GMDS_HUMAN GMDS_HUMAN]] Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose.
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__TOC__
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</StructureSection>
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[[Category: GDP-mannose 4,6-dehydratase]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Delft, F von]]
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[[Category: Edwards, A]]
[[Category: Johansson, C]]
[[Category: Johansson, C]]
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[[Category: Krojer, T]]
[[Category: Nidetzky, B]]
[[Category: Nidetzky, B]]
[[Category: Oppermann, U]]
[[Category: Oppermann, U]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Pfeiffer, M]]
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[[Category: Edwards, A]]
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[[Category: Structural genomic]]
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[[Category: Krojer, T]]
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[[Category: Lyase]]
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[[Category: Von Delft, F]]
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[[Category: Sgc]]
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[[Category: Bountra, C]]
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Revision as of 07:43, 18 July 2018

Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man

6gpl, resolution 1.76Å

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