6gy4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the N-terminal KH domain of human BICC1== | |
| - | + | <StructureSection load='6gy4' size='340' side='right' caption='[[6gy4]], [[Resolution|resolution]] 1.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gy4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GY4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XPE:3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL'>XPE</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gy4 OCA], [http://pdbe.org/6gy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gy4 RCSB], [http://www.ebi.ac.uk/pdbsum/6gy4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gy4 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| + | [[http://www.uniprot.org/uniprot/BICC1_HUMAN BICC1_HUMAN]] Autosomal dominant polycystic kidney disease. Disease susceptibility is associated with variations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BICC1_HUMAN BICC1_HUMAN]] Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development.<ref>PMID:21922595</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
[[Category: Burgess-Brown, N]] | [[Category: Burgess-Brown, N]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Edwards, A]] | ||
| + | [[Category: Gileadi, O]] | ||
| + | [[Category: Katis, V L]] | ||
| + | [[Category: Newman, J A]] | ||
[[Category: Shrestha, L]] | [[Category: Shrestha, L]] | ||
| - | [[Category: | + | [[Category: Bicaudal]] |
| - | [[Category: | + | [[Category: Kh domain]] |
| - | [[Category: | + | [[Category: Rna binding]] |
| - | [[Category: | + | [[Category: Rna binding protein]] |
| - | [[Category: | + | [[Category: Transcription]] |
Current revision
Crystal structure of the N-terminal KH domain of human BICC1
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