Interferon receptor

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Line 29: Line 29:
**[[3se4]] – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-ω 1 <br />
**[[3se4]] – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-ω 1 <br />
**[[3wcy]] – INFAR1 ectodomain + interferon-β - mouse <br />
**[[3wcy]] – INFAR1 ectodomain + interferon-β - mouse <br />
 +
**[[4po6]] – hINFDR1 residues 475-507 + TYK2 <br />
*Interferon γ receptor
*Interferon γ receptor
Line 41: Line 42:
**[[3og4]], [[3og6]] – hINFDR1 extracellular domain + interleukin-29 <br />
**[[3og4]], [[3og6]] – hINFDR1 extracellular domain + interleukin-29 <br />
**[[5t5w]] – hINFDR1 extracellular domain + interleukin-10 receptor + interferon-δ 3 <br />
**[[5t5w]] – hINFDR1 extracellular domain + interleukin-10 receptor + interferon-δ 3 <br />
-
**[[5t5w]], [[5ixd]] – hINFDR1 residues 260-307 + JAK1 <br />
+
**[[5t5w]], [[5ixd]], [[5l04]] – hINFDR1 residues 260-307 + JAK1 <br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 06:14, 23 July 2018

Structure of interferon α/β receptor β chain ectodomain (yellow) complex with interferon-α 2 (pink) and Cl- ion (green) (PDB entry 3s9d)

Drag the structure with the mouse to rotate

3D structures of interferon receptor

Updated on 23-July-2018

References

  1. Uze G, Schreiber G, Piehler J, Pellegrini S. The receptor of the type I interferon family. Curr Top Microbiol Immunol. 2007;316:71-95. PMID:17969444
  2. Pestka S, Kotenko SV, Muthukumaran G, Izotova LS, Cook JR, Garotta G. The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor. Cytokine Growth Factor Rev. 1997 Sep;8(3):189-206. PMID:9462485
  3. Lefevre F, Guillomot M, D'Andrea S, Battegay S, La Bonnardiere C. Interferon-delta: the first member of a novel type I interferon family. Biochimie. 1998 Aug-Sep;80(8-9):779-88. PMID:9865499
  4. . PMID:16451483
  5. Santiago-Raber ML, Baccala R, Haraldsson KM, Choubey D, Stewart TA, Kono DH, Theofilopoulos AN. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J Exp Med. 2003 Mar 17;197(6):777-88. PMID:12642605 doi:http://dx.doi.org/10.1084/jem.20021996
  6. Jouanguy E, Lamhamedi-Cherradi S, Lammas D, Dorman SE, Fondaneche MC, Dupuis S, Doffinger R, Altare F, Girdlestone J, Emile JF, Ducoulombier H, Edgar D, Clarke J, Oxelius VA, Brai M, Novelli V, Heyne K, Fischer A, Holland SM, Kumararatne DS, Schreiber RD, Casanova JL. A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection. Nat Genet. 1999 Apr;21(4):370-8. PMID:10192386 doi:http://dx.doi.org/10.1038/7701

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Michal Harel

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