Interleukin-1 receptor-associated kinase

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*IRAK1
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**[[6bfn]] – hIRAK1 residues 194-530 - human<br />
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*IRAK2
*IRAK2
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**[[3mop]] – hIRAK2 DEATH domain + hIRAK4 DEATH domain + MYD88 - human<br />
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**[[3mop]] – hIRAK2 DEATH domain + hIRAK4 DEATH domain + MYD88 <br />
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*IRAK3 DEATH domain residues 4-106
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**[[5uke]] – hIRAK3 DEATH domain (mutant) - NMR<br />
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*IRAK4
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*IRAK4 kinase domain residues 30-336; DEATH domain residues 4-106
**[[2nru]], [[2nry]], [[2oib]], [[2o8y]], [[4rmz]] – hIRAK4 kinase domain - human<br />
**[[2nru]], [[2nry]], [[2oib]], [[2o8y]], [[4rmz]] – hIRAK4 kinase domain - human<br />
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**[[2a9i]] - mIRAK4 DEATH domain<br />
**[[2a9i]] - mIRAK4 DEATH domain<br />
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br />
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br />
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**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]] - hIRAK4 kinase domain + inhibitor<br />
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**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]], [[6f3d]], [[6f3e]], [[6f3g]], [[6f3i]] - hIRAK4 kinase domain + inhibitor<br />
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**[[5w84]], [[5w85]], [[5k72]], [[5k75]], [[5k76]], [[5k7g]], [[5k7i]] - hIRAK4 residues 154-460 + inhibitor<br />
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br />
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br />
**[[3mop]] - hIRAK4 DEATH domain + hIRAK2 DEATH domain + MYD88<br />
**[[3mop]] - hIRAK4 DEATH domain + hIRAK2 DEATH domain + MYD88<br />

Revision as of 08:14, 23 July 2018

Mouse IRAK4 death domain complex with Mn+2 ion , 2a9i

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3D structures of IRAK4

Updated on 23-July-2018

References

  1. Cao Z, Henzel WJ, Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 1996 Feb 23;271(5252):1128-31. PMID:8599092

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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