Kdo-8-phosphate synthase

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<StructureSection load='3fyp' size='450' side='right' scene='52/525184/Cv/2' caption='Metallo Kdo-8-phosphate synthase tetramer complex with phosphoenolpyruvate, glycerol, Cl- (green), Na+ (large purple) and Mn+2 (small purple) ion, [[3fyp]]'>
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<StructureSection load='3fyp' size='350' side='right' scene='52/525184/Cv/2' caption='Metallo Kdo-8-phosphate synthase tetramer complex with phosphoenolpyruvate, glycerol, Cl- (green), Na+ (large purple) and Mn+2 (small purple) ion, [[3fyp]]'>
== Function ==
== Function ==
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**[[3sz8]] – BpKPS-2 – ''Burkholderia pseudomallei''<br />
**[[3sz8]] – BpKPS-2 – ''Burkholderia pseudomallei''<br />
**[[4lu0]] – KPS – ''Pseudomonas aeruginosa''<br />
**[[4lu0]] – KPS – ''Pseudomonas aeruginosa''<br />
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**[[4z1a]] – HpKPS – ''Helicobacter pylori''<br />
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**[[4z1b]] - HpKPS (mutant)<br />
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**[[4z1c]] - HpKPS + Cd<br />
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**[[6bng]] – KPS – ''Acinetobacter baumannii''<br />
*''Metallo Kdo8P binary complex''
*''Metallo Kdo8P binary complex''
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**[[3e12]] - AaKPS + Kdo-8-P + Cu<br />
**[[3e12]] - AaKPS + Kdo-8-P + Cu<br />
**[[2nxi]], [[1fwn]] - AaKPS + PEP<br />
**[[2nxi]], [[1fwn]] - AaKPS + PEP<br />
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**[[2nwr]], [[2nxh]] - AaKPS (mutant) + PEP<br />
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**[[2nwr]], [[2nxh]] - AaKPS (mutant) + PEP<br />
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**[[4z1d]] - HpKPS + PEP + Zn<br />
**[[3fyp]] - NmKPS (mutant) + PEP + Mn<br />
**[[3fyp]] - NmKPS (mutant) + PEP + Mn<br />
**[[3tmq]] - BpKPS + arabinose-5-phosphate<br />
**[[3tmq]] - BpKPS + arabinose-5-phosphate<br />

Revision as of 09:35, 24 July 2018

Metallo Kdo-8-phosphate synthase tetramer complex with phosphoenolpyruvate, glycerol, Cl- (green), Na+ (large purple) and Mn+2 (small purple) ion, 3fyp

Drag the structure with the mouse to rotate

3D structures of Kdo-8-phosphate synthase

Updated on 24-July-2018

References

  1. ↑ Krosky DJ, Alm R, Berg M, Carmel G, Tummino PJ, Xu B, Yang W. Helicobacter pylori 3-deoxy-D-manno-octulosonate-8-phosphate (KDO-8-P) synthase is a zinc-metalloenzyme. Biochim Biophys Acta. 2002 Feb 11;1594(2):297-306. PMID:11904225
  2. ↑ Cochrane FC, Cookson TV, Jameson GB, Parker EJ. Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase. J Mol Biol. 2009 Jul 24;390(4):646-61. Epub 2009 May 15. PMID:19447118 doi:10.1016/j.jmb.2009.05.014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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