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Metabotropic glutamate receptor
From Proteopedia
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*'''Metabotropic glutamate receptor 1''' and '''metabotropic glutamate receptor 5''' belong to group I and activate phospholipase C. For details see [[Metabotropic glutamate receptor 5]].<br /> | *'''Metabotropic glutamate receptor 1''' and '''metabotropic glutamate receptor 5''' belong to group I and activate phospholipase C. For details see [[Metabotropic glutamate receptor 5]].<br /> | ||
*'''Metabotropic glutamate receptor 2''' and '''metabotropic glutamate receptor 3''' belong to group II and inhibit the cyclic AMP cascade.<br /> | *'''Metabotropic glutamate receptor 2''' and '''metabotropic glutamate receptor 3''' belong to group II and inhibit the cyclic AMP cascade.<br /> | ||
| - | *'''Metabotropic glutamate receptor 7''' and '''metabotropic glutamate receptor 8'''belong to group III and inhibits adenylate cyclase activity.<br /> | + | *'''Metabotropic glutamate receptor 7''' and '''metabotropic glutamate receptor 8''' belong to group III and inhibits adenylate cyclase activity.<br /> |
Articles in Proteopedia concerning Toll-like Receptors include: | Articles in Proteopedia concerning Toll-like Receptors include: | ||
Revision as of 09:54, 6 August 2018
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3D structures of metabotropic glutamate receptor
Updated on 06-August-2018
See Also
Membrane Channels & Pumps
Ionotropic_Glutamate_Receptors
Alzheimer's Disease
References
- ↑ Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev. 2010 Sep;62(3):405-96. doi: 10.1124/pr.109.002451. PMID:20716669 doi:http://dx.doi.org/10.1124/pr.109.002451
- ↑ Johnson KA, Conn PJ, Niswender CM. Glutamate receptors as therapeutic targets for Parkinson's disease. CNS Neurol Disord Drug Targets. 2009 Dec;8(6):475-91. PMID:19702565
- ↑ Niswender CM, Conn PJ. Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu Rev Pharmacol Toxicol. 2010;50:295-322. doi:, 10.1146/annurev.pharmtox.011008.145533. PMID:20055706 doi:http://dx.doi.org/10.1146/annurev.pharmtox.011008.145533
- ↑ Kunishima N, Shimada Y, Tsuji Y, Sato T, Yamamoto M, Kumasaka T, Nakanishi S, Jingami H, Morikawa K. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature. 2000 Oct 26;407(6807):971-7. PMID:11069170 doi:10.1038/35039564
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