5oll
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of gurmarin, a sweet taste suppressing polypeptide== | |
| - | + | <StructureSection load='5oll' size='340' side='right' caption='[[5oll]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5oll]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OLL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OLL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oll OCA], [http://pdbe.org/5oll PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oll RCSB], [http://www.ebi.ac.uk/pdbsum/5oll PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oll ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GUR_GYMSY GUR_GYMSY]] Suppresses strongly the sweet taste responses in the rat with high specificity to sucrose, glucose, glycine, and saccharin. This effect is reversible, but complete recovery of the suppressed responses required at least 3h. Gurmarin showed no effect or only a very weak effect on the sweet taste sensation in humans. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Briand, L]] | ||
[[Category: Legrand, P]] | [[Category: Legrand, P]] | ||
[[Category: Neiers, F]] | [[Category: Neiers, F]] | ||
| - | [[Category: Briand, L]] | ||
[[Category: Roblin, P]] | [[Category: Roblin, P]] | ||
[[Category: Sigoillot, M]] | [[Category: Sigoillot, M]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Gurmarin]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Knottin]] | ||
| + | [[Category: Plant protein]] | ||
| + | [[Category: Sweet]] | ||
| + | [[Category: Taste]] | ||
Revision as of 21:15, 9 August 2018
Crystal structure of gurmarin, a sweet taste suppressing polypeptide
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Categories: Briand, L | Legrand, P | Neiers, F | Roblin, P | Sigoillot, M | Gpcr | Gurmarin | Inhibitor | Knottin | Plant protein | Sweet | Taste
