5xxq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of RBBP4: ZNF827 and its function in telomere== | |
| - | + | <StructureSection load='5xxq' size='340' side='right' caption='[[5xxq]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5xxq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XXQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xxq OCA], [http://pdbe.org/5xxq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xxq RCSB], [http://www.ebi.ac.uk/pdbsum/5xxq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xxq ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RBBP4_HUMAN RBBP4_HUMAN]] Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.<ref>PMID:10866654</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Shi, Y]] | ||
[[Category: Sun, A]] | [[Category: Sun, A]] | ||
| - | [[Category: | + | [[Category: Rbap48]] |
| + | [[Category: Rbbp4]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Wd40]] | ||
| + | [[Category: Znf827]] | ||
Revision as of 21:41, 9 August 2018
Crystal structure of RBBP4: ZNF827 and its function in telomere
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Categories: Shi, Y | Sun, A | Rbap48 | Rbbp4 | Transcription | Wd40 | Znf827
