6gb2
From Proteopedia
(Difference between revisions)
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- | ''' | + | {{Large structure}} |
- | + | ==Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 39S ribosomal subunit.== | |
- | + | <StructureSection load='6gb2' size='340' side='right' caption='[[6gb2]], [[Resolution|resolution]] 3.20Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6gb2]] is a 62 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GB2 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gb2 OCA], [http://pdbe.org/6gb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gb2 RCSB], [http://www.ebi.ac.uk/pdbsum/6gb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gb2 ProSAT]</span></td></tr> | |
- | [[Category: | + | </table> |
+ | {{Large structure}} | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/IF2M_HUMAN IF2M_HUMAN]] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Sus scrofa]] | ||
+ | [[Category: Ban, N]] | ||
+ | [[Category: Boehringer, D]] | ||
+ | [[Category: Kummer, E]] | ||
+ | [[Category: Leibundgut, M]] | ||
+ | [[Category: Initiation factor if2]] | ||
+ | [[Category: Membrane targeting]] | ||
+ | [[Category: Mitochondria]] | ||
+ | [[Category: Ribosome]] | ||
+ | [[Category: Translation initiation]] |
Revision as of 21:57, 9 August 2018
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Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 39S ribosomal subunit.
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