2p0b
From Proteopedia
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|PDB= 2p0b |SIZE=350|CAPTION= <scene name='initialview01'>2p0b</scene>, resolution 1.740Å | |PDB= 2p0b |SIZE=350|CAPTION= <scene name='initialview01'>2p0b</scene>, resolution 1.740Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=HEC:HEME C'>HEC</scene> | + | |LIGAND= <scene name='pdbligand=HEC:HEME+C'>HEC</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= nrfB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]) | |GENE= nrfB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2ozy|2OZY]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0b OCA], [http://www.ebi.ac.uk/pdbsum/2p0b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p0b RCSB]</span> | ||
}} | }} | ||
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[[Category: Hemmings, A M.]] | [[Category: Hemmings, A M.]] | ||
[[Category: Richardson, D J.]] | [[Category: Richardson, D J.]] | ||
| - | [[Category: HEC]] | ||
[[Category: electron transport]] | [[Category: electron transport]] | ||
[[Category: pentaheme c-type cytochrome]] | [[Category: pentaheme c-type cytochrome]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:26:03 2008'' |
Revision as of 01:26, 31 March 2008
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| , resolution 1.740Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | nrfB (Escherichia coli) | ||||||
| Related: | 2OZY
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of chemically-reduced E.coli nrfB
Overview
NrfB is a small pentahaem electron-transfer protein widely involved in the respiratory reduction of nitrite or nitric oxide to ammonia, processes that provide energy for anaerobic metabolism in many enteric bacteria and also serve to detoxify these reactive nitrogen species. The X-ray crystal structure of Escherichia coli NrfB is presented at 1.74 A (1 A=0.1 nm) resolution. The architecture of the protein is that of a 40 A 'nanowire' in which the five haems are positioned within 6 A of each other along a polypeptide scaffold. During nitrite reduction, the physiological role of NrfB is to mediate electron transfer to another pentahaem protein, NrfA, the enzyme that catalyses periplasmic nitrite or nitric oxide reduction. Protein-protein interaction studies suggest NrfA and NrfB can form a 20-haem NrfA2-NrfB2 heterotetrameric complex.
About this Structure
2P0B is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
The crystal structure of the pentahaem c-type cytochrome NrfB and characterization of its solution-state interaction with the pentahaem nitrite reductase NrfA., Clarke TA, Cole JA, Richardson DJ, Hemmings AM, Biochem J. 2007 Aug 15;406(1):19-30. PMID:17521287
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