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5xfj

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<StructureSection load='5xfj' size='340' side='right' caption='[[5xfj]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
<StructureSection load='5xfj' size='340' side='right' caption='[[5xfj]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5xfj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XFJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XFJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LF:2-[4-[E-2-[5-[(1R)-1-[3,5-BIS(CHLORANYL)PYRIDIN-4-YL]ETHOXY]-1H-INDAZOL-3-YL]ETHENYL]PYRAZOL-1-YL]ETHANOL'>6LF</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LF:2-[4-[E-2-[5-[(1R)-1-[3,5-BIS(CHLORANYL)PYRIDIN-4-YL]ETHOXY]-1H-INDAZOL-3-YL]ETHENYL]PYRAZOL-1-YL]ETHANOL'>6LF</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xff|5xff]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xff|5xff]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FGFR4, JTK2, TKF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xfj OCA], [http://pdbe.org/5xfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xfj RCSB], [http://www.ebi.ac.uk/pdbsum/5xfj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xfj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xfj OCA], [http://pdbe.org/5xfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xfj RCSB], [http://www.ebi.ac.uk/pdbsum/5xfj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xfj ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Chen, Y]]
[[Category: Chen, Y]]

Revision as of 16:35, 15 August 2018

Crystal structure of LY2874455 in complex of FGFR4 gatekeeper mutation (V550M)

5xfj, resolution 3.25Å

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