6chg
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the yeast COMPASS catalytic module== | |
| - | + | <StructureSection load='6chg' size='340' side='right' caption='[[6chg]], [[Resolution|resolution]] 2.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6chg]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CHG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6chg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6chg OCA], [http://pdbe.org/6chg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6chg RCSB], [http://www.ebi.ac.uk/pdbsum/6chg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6chg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SET1_KLULA SET1_KLULA]] Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Histone-lysine N-methyltransferase]] | ||
| + | [[Category: Hsu, P L]] | ||
| + | [[Category: Li, H]] | ||
| + | [[Category: Zheng, N]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Enzyme]] | ||
| + | [[Category: Histone]] | ||
| + | [[Category: S-adenosylmethionine]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:05, 22 August 2018
Crystal structure of the yeast COMPASS catalytic module
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