Poly(A) RNA polymerase
From Proteopedia
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'''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis<ref>PMID:17072891</ref>. Cid1 is found in fission yeast. Cid1 exists in 3 forms: '''apo I''' consists of 4 subunits; '''apo II''' consists of 2 subunits; '''UTP-bound''' form consists of 4 subunits. <br /> | '''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis<ref>PMID:17072891</ref>. Cid1 is found in fission yeast. Cid1 exists in 3 forms: '''apo I''' consists of 4 subunits; '''apo II''' consists of 2 subunits; '''UTP-bound''' form consists of 4 subunits. <br /> | ||
| - | '''Poly(A) RNA polymerase Gld2''' is responsible for poly(A) tail lengthening. Gld2 activity in the brain is required for long-term memory<ref>PMID: | + | '''Poly(A) RNA polymerase Gld2''' is responsible for poly(A) tail lengthening. Gld2 activity in the brain is required for long-term memory<ref>PMID:15987818</ref>. |
== Structural highlights == | == Structural highlights == | ||
Revision as of 08:05, 23 August 2018
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3D Structures of poly(A) RNA polymerase protein Cid1
Updated on 23-August-2018
References
- ↑ Stevenson AL, Norbury CJ. The Cid1 family of non-canonical poly(A) polymerases. Yeast. 2006 Oct 15;23(13):991-1000. PMID:17072891 doi:http://dx.doi.org/10.1002/yea.1408
- ↑ Rouhana L, Wang L, Buter N, Kwak JE, Schiltz CA, Gonzalez T, Kelley AE, Landry CF, Wickens M. Vertebrate GLD2 poly(A) polymerases in the germline and the brain. RNA. 2005 Jul;11(7):1117-30. PMID:15987818 doi:http://dx.doi.org/11/7/1117
- ↑ Yates LA, Fleurdepine S, Rissland OS, De Colibus L, Harlos K, Norbury CJ, Gilbert RJ. Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat Struct Mol Biol. 2012 Jul 1. doi: 10.1038/nsmb.2329. PMID:22751018 doi:10.1038/nsmb.2329
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