Pre-mRNA-splicing factor
From Proteopedia
(Difference between revisions)
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- | <StructureSection load='' size=' | + | <StructureSection load='' size='350' side='right' caption='Yeast pre-mRNA-splicing factor 8 (green) complex with AAR2 (cyan) (PDB entry [[3zef]])' scene='46/462200/Cv/1'> |
__TOC__ | __TOC__ | ||
== Function == | == Function == | ||
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**[[1x5t]] - hPrp subunit 4 – NMR<BR /> | **[[1x5t]] - hPrp subunit 4 – NMR<BR /> | ||
**[[5gvq]] - hPrp subunit 4 RNA-binding domain – NMR<BR /> | **[[5gvq]] - hPrp subunit 4 RNA-binding domain – NMR<BR /> | ||
+ | **[[6en4]] - hPrp subunits 1,3,5 + SF3B14B<br /> | ||
+ | **[[5ife]] - hPrp subunits 1,3,5 + PHD finger-like protein 5A <br /> | ||
+ | **[[5zya]] - hPrp subunits 1,3,5 + PHD finger-like protein 5A + splicing modulator<br /> | ||
*Pre-mRNA-splicing factor 8 | *Pre-mRNA-splicing factor 8 | ||
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**[[3jb9]] – yPrp <br /> | **[[3jb9]] – yPrp <br /> | ||
- | **[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5wsg]] – yPrp - CryoEM<br /> | + | **[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5wsg]], [[6g90]], [[6exn]], [[6bk8]], [[5ylz]], [[5y88]] – yPrp - CryoEM<br /> |
**[[3jcr]], [[5o9z]] – hPrp - CryoEM<br /> | **[[3jcr]], [[5o9z]] – hPrp - CryoEM<br /> | ||
Revision as of 09:52, 26 August 2018
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3D Structures of pre-mRNA splicing factors
Updated on 26-August-2018
References
- ↑ Misteli T, Spector DL. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell. 1999 Jun;3(6):697-705. PMID:10394358
- ↑ McKie AB, McHale JC, Keen TJ, Tarttelin EE, Goliath R, van Lith-Verhoeven JJ, Greenberg J, Ramesar RS, Hoyng CB, Cremers FP, Mackey DA, Bhattacharya SS, Bird AC, Markham AF, Inglehearn CF. Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum Mol Genet. 2001 Jul 15;10(15):1555-62. PMID:11468273