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5op1

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m (Protected "5op1" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5op1 is ON HOLD until Paper Publication
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==Designed Ankyrin Repeat Protein (DARPin) A4 in complex with Lysozyme==
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<StructureSection load='5op1' size='340' side='right' caption='[[5op1]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5op1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OP1 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5op1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5op1 OCA], [http://pdbe.org/5op1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5op1 RCSB], [http://www.ebi.ac.uk/pdbsum/5op1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5op1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Edmond, S]]
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[[Category: Fischer, G]]
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[[Category: Hogan, B J]]
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[[Category: Hollfelder, F]]
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[[Category: Houlihan, G]]
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[[Category: Huovinen, T T.K]]
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[[Category: Hyvonen, M]]
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[[Category: Darpin]]
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[[Category: De novo protein]]
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[[Category: Designed protein]]
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[[Category: Directed evolution]]
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[[Category: Protein protein complex]]

Revision as of 07:17, 29 August 2018

Designed Ankyrin Repeat Protein (DARPin) A4 in complex with Lysozyme

5op1, resolution 2.28Å

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