2pfh
From Proteopedia
(Difference between revisions)
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|PDB= 2pfh |SIZE=350|CAPTION= <scene name='initialview01'>2pfh</scene>, resolution 0.85Å | |PDB= 2pfh |SIZE=350|CAPTION= <scene name='initialview01'>2pfh</scene>, resolution 0.85Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FID:(2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE'>FID</scene>, <scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span> |
|GENE= AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1uso|1USO]], [[1pwd|1PWD]], [[2i16|2I16]], [[2i17|2I17]], [[2acr|2ACR]], [[2acq|2ACQ]], [[2pev|2PEV]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfh OCA], [http://www.ebi.ac.uk/pdbsum/2pfh PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pfh RCSB]</span> | ||
}} | }} | ||
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[[Category: Petrova, T.]] | [[Category: Petrova, T.]] | ||
[[Category: Podjarny, A.]] | [[Category: Podjarny, A.]] | ||
| - | [[Category: CIT]] | ||
| - | [[Category: CL]] | ||
| - | [[Category: FID]] | ||
| - | [[Category: LDT]] | ||
| - | [[Category: NDP]] | ||
[[Category: fidarestat]] | [[Category: fidarestat]] | ||
[[Category: idd594]] | [[Category: idd594]] | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:35:12 2008'' |
Revision as of 01:35, 31 March 2008
| |||||||
| , resolution 0.85Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , | ||||||
| Gene: | AKR1B1, ALDR1 (Homo sapiens) | ||||||
| Activity: | Aldehyde reductase, with EC number 1.1.1.21 | ||||||
| Related: | 1USO, 1PWD, 2I16, 2I17, 2ACR, 2ACQ, 2PEV
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is less than concentration of IDD594.
About this Structure
2PFH is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:35:12 2008
