4wxi
From Proteopedia
(Difference between revisions)
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<StructureSection load='4wxi' size='340' side='right' caption='[[4wxi]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='4wxi' size='340' side='right' caption='[[4wxi]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4wxi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4wxi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WXI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WXI FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VM:TRANS-N-{(1S)-1-[4-(3-AMINO-2H-INDAZOL-6-YL)PYRIDIN-2-YL]-2-PHENYLETHYL}-4-(AMINOMETHYL)CYCLOHEXANECARBOXAMIDE'>3VM</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VM:TRANS-N-{(1S)-1-[4-(3-AMINO-2H-INDAZOL-6-YL)PYRIDIN-2-YL]-2-PHENYLETHYL}-4-(AMINOMETHYL)CYCLOHEXANECARBOXAMIDE'>3VM</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">F11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wxi OCA], [http://pdbe.org/4wxi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wxi RCSB], [http://www.ebi.ac.uk/pdbsum/4wxi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wxi ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wxi OCA], [http://pdbe.org/4wxi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wxi RCSB], [http://www.ebi.ac.uk/pdbsum/4wxi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wxi ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Wei, A]] | [[Category: Wei, A]] | ||
[[Category: Blood coagulation factor]] | [[Category: Blood coagulation factor]] | ||
Revision as of 07:44, 29 August 2018
FACTOR XIA IN COMPLEX WITH THE INHIBITOR trans-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)pyridin-2-yl]-2-phenylethyl}-4-(aminomethyl)cyclohexanecarboxamide
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