2pit
From Proteopedia
(Difference between revisions)
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|PDB= 2pit |SIZE=350|CAPTION= <scene name='initialview01'>2pit</scene>, resolution 1.76Å | |PDB= 2pit |SIZE=350|CAPTION= <scene name='initialview01'>2pit</scene>, resolution 1.76Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=4HY:[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC+ACID'>4HY</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2pin|2PIN]], [[2pio|2PIO]], [[2pip|2PIP]], [[2piq|2PIQ]], [[2pir|2PIR]], [[2piu|2PIU]], [[2piv|2PIV]], [[2piw|2PIW]], [[2pix|2PIX]], [[2pkl|2PKL]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pit OCA], [http://www.ebi.ac.uk/pdbsum/2pit PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pit RCSB]</span> | ||
}} | }} | ||
'''Androgen receptor LBD with small molecule''' | '''Androgen receptor LBD with small molecule''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Androgen insensitivity OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Breast cancer, male, with Reifenstein syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Hypospadias, perineal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Spinal and bulbar muscular atrophy of Kennedy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Guy, R K.]] | [[Category: Guy, R K.]] | ||
[[Category: Webb, P.]] | [[Category: Webb, P.]] | ||
| - | [[Category: 4HY]] | ||
| - | [[Category: DHT]] | ||
| - | [[Category: SO4]] | ||
[[Category: androgen receptor coactivator binding inhibitors af-2]] | [[Category: androgen receptor coactivator binding inhibitors af-2]] | ||
[[Category: hormone receptor]] | [[Category: hormone receptor]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:36:28 2008'' |
Revision as of 01:36, 31 March 2008
| |||||||
| , resolution 1.76Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | AR, DHTR, NR3C4 (Homo sapiens) | ||||||
| Related: | 2PIN, 2PIO, 2PIP, 2PIQ, 2PIR, 2PIU, 2PIV, 2PIW, 2PIX, 2PKL
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Androgen receptor LBD with small molecule
About this Structure
2PIT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:36:28 2008
