2qfa

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==Crystal structure of a Survivin-Borealin-INCENP core complex==
==Crystal structure of a Survivin-Borealin-INCENP core complex==
<StructureSection load='2qfa' size='340' side='right' caption='[[2qfa]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='2qfa' size='340' side='right' caption='[[2qfa]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BIRC5, API4, IAP4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), CDCA8, PESCRG3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), INCENP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BIRC5, API4, IAP4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), CDCA8, PESCRG3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), INCENP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qfa OCA], [http://pdbe.org/2qfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qfa RCSB], [http://www.ebi.ac.uk/pdbsum/2qfa PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qfa OCA], [http://pdbe.org/2qfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qfa RCSB], [http://www.ebi.ac.uk/pdbsum/2qfa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qfa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qf/2qfa_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qf/2qfa_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qfa ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Borealin|Borealin]]
*[[Centromere protein|Centromere protein]]
*[[Centromere protein|Centromere protein]]
*[[Survivin|Survivin]]
*[[Survivin|Survivin]]
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[[Category: Lindner, D]]
[[Category: Lindner, D]]
[[Category: Nigg, E A]]
[[Category: Nigg, E A]]
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[[Category: Alternative splicing]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
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[[Category: Centromere]]
[[Category: Centromere]]
[[Category: Chromosomal protein]]
[[Category: Chromosomal protein]]
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[[Category: Coiled coil]]
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[[Category: Cytoplasm]]
[[Category: Long helix]]
[[Category: Long helix]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
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[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
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[[Category: Polymorphism]]
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Thiol protease inhibitor]]
[[Category: Thiol protease inhibitor]]
[[Category: Three-helical-bundle]]
[[Category: Three-helical-bundle]]
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[[Category: Zinc]]

Revision as of 08:43, 29 August 2018

Crystal structure of a Survivin-Borealin-INCENP core complex

2qfa, resolution 1.40Å

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