5yam

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m (Protected "5yam" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5yam is ON HOLD until Sep 01 2019
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==Solution structure of mice Met-CCL5/RANTES==
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<StructureSection load='5yam' size='340' side='right' caption='[[5yam]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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Authors: Chen, Y.-C., Chen, S.-P., Lee, Y.-Z., Sue, S.-C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5yam]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YAM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YAM FirstGlance]. <br>
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Description: Solution structure of mice Met-CCL5/RANTES
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cmd|5cmd]], [[1eqt|1eqt]]</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yam OCA], [http://pdbe.org/5yam PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yam RCSB], [http://www.ebi.ac.uk/pdbsum/5yam PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yam ProSAT]</span></td></tr>
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[[Category: Sue, S.-C]]
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</table>
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[[Category: Chen, Y.-C]]
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== Function ==
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[[Category: Chen, S.-P]]
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[[http://www.uniprot.org/uniprot/CCL5_MOUSE CCL5_MOUSE]] Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.[UniProtKB:P13501]
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[[Category: Lee, Y.-Z]]
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__TOC__
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</StructureSection>
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[[Category: Chen, S P]]
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[[Category: Chen, Y C]]
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[[Category: Lee, Y Z]]
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[[Category: Sue, S C]]
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[[Category: Antagonist]]
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[[Category: Chemokine]]
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[[Category: Cytokine]]
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[[Category: Dimer]]
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[[Category: Heparin]]
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[[Category: Inflammatory]]

Revision as of 10:00, 5 September 2018

Solution structure of mice Met-CCL5/RANTES

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