Rho guanine nucleotide exchange factor

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**[[1x6b]] – hGEF SH3 domain - NMR<br />
**[[1x6b]] – hGEF SH3 domain - NMR<br />
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*GEF guanine nucleotide exchange factor 18
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**[[6bcb]] – mGEF + transforming protein RhoA<br />
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*GEF guanine nucleotide exchange factor 28
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**[[6bc1]] – hGEF + Ras-related C3 botulinum toxin substrate 1<br />
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**[[6bc0]] – hGEF + transforming protein RhoA<br />
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}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:21, 6 September 2018

Human Rho guanine nucleotide exchange factor 11 DH/PH domain (grey) complex with transforming protein RhoA (cyan), GSP and Mg+2 ion (green) (PDB code 3kz1)

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3D Structures of Rho guanine nucleotide exchange factor

Updated on 06-September-2018

References

  1. Cherfils J, Zeghouf M. Regulation of small GTPases by GEFs, GAPs, and GDIs. Physiol Rev. 2013 Jan;93(1):269-309. doi: 10.1152/physrev.00003.2012. PMID:23303910 doi:http://dx.doi.org/10.1152/physrev.00003.2012
  2. Cook DR, Rossman KL, Der CJ. Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease. Oncogene. 2014 Jul 31;33(31):4021-35. doi: 10.1038/onc.2013.362. Epub 2013 Sep, 16. PMID:24037532 doi:http://dx.doi.org/10.1038/onc.2013.362

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Michal Harel, Joel L. Sussman

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