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6ay9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide== | |
| - | + | <StructureSection load='6ay9' size='340' side='right' caption='[[6ay9]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ay9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AY9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xfx|4xfx]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ay9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay9 OCA], [http://pdbe.org/6ay9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ay9 RCSB], [http://www.ebi.ac.uk/pdbsum/6ay9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CPSF6_HUMAN CPSF6_HUMAN]] Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:21295486</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gres, A T]] | ||
| + | [[Category: Kirby, K A]] | ||
| + | [[Category: Sarafianos, S G]] | ||
| + | [[Category: Cpsf6 complex]] | ||
| + | [[Category: Hexamer]] | ||
| + | [[Category: Hiv-1 capsid protein]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 07:33, 12 September 2018
Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide
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