2pw8
From Proteopedia
(Difference between revisions)
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|PDB= 2pw8 |SIZE=350|CAPTION= <scene name='initialview01'>2pw8</scene>, resolution 1.840Å | |PDB= 2pw8 |SIZE=350|CAPTION= <scene name='initialview01'>2pw8</scene>, resolution 1.840Å | ||
|SITE= | |SITE= | ||
- | |LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene> | + | |LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
+ | |DOMAIN= | ||
+ | |RELATEDENTRY=[[4htc|4HTC]] | ||
+ | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pw8 OCA], [http://www.ebi.ac.uk/pdbsum/2pw8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pw8 RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of sulfo-hirudin complexed to thrombin''' | '''Crystal structure of sulfo-hirudin complexed to thrombin''' | ||
- | |||
- | ==Disease== | ||
- | Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Liu, W.]] | [[Category: Liu, W.]] | ||
[[Category: Schultz, P G.]] | [[Category: Schultz, P G.]] | ||
- | [[Category: NA]] | ||
- | [[Category: NI]] | ||
[[Category: hirudin]] | [[Category: hirudin]] | ||
[[Category: hydrolase]] | [[Category: hydrolase]] | ||
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[[Category: thrombin]] | [[Category: thrombin]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:41:34 2008'' |
Revision as of 01:41, 31 March 2008
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, resolution 1.840Å | |||||||
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Ligands: | , , | ||||||
Related: | 4HTC
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Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Crystal structure of sulfo-hirudin complexed to thrombin
About this Structure
2PW8 is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin., Liu CC, Brustad E, Liu W, Schultz PG, J Am Chem Soc. 2007 Sep 5;129(35):10648-9. Epub 2007 Aug 9. PMID:17685615
Page seeded by OCA on Mon Mar 31 04:41:34 2008