2pw8

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|PDB= 2pw8 |SIZE=350|CAPTION= <scene name='initialview01'>2pw8</scene>, resolution 1.840&Aring;
|PDB= 2pw8 |SIZE=350|CAPTION= <scene name='initialview01'>2pw8</scene>, resolution 1.840&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene> and <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
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|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=[[4htc|4HTC]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pw8 OCA], [http://www.ebi.ac.uk/pdbsum/2pw8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pw8 RCSB]</span>
}}
}}
'''Crystal structure of sulfo-hirudin complexed to thrombin'''
'''Crystal structure of sulfo-hirudin complexed to thrombin'''
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==Disease==
 
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Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
 
==About this Structure==
==About this Structure==
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[[Category: Liu, W.]]
[[Category: Liu, W.]]
[[Category: Schultz, P G.]]
[[Category: Schultz, P G.]]
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[[Category: NA]]
 
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[[Category: NI]]
 
[[Category: hirudin]]
[[Category: hirudin]]
[[Category: hydrolase]]
[[Category: hydrolase]]
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[[Category: thrombin]]
[[Category: thrombin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:18:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:41:34 2008''

Revision as of 01:41, 31 March 2008


PDB ID 2pw8

Drag the structure with the mouse to rotate
, resolution 1.840Å
Ligands: , ,
Related: 4HTC


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of sulfo-hirudin complexed to thrombin


About this Structure

2PW8 is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin., Liu CC, Brustad E, Liu W, Schultz PG, J Am Chem Soc. 2007 Sep 5;129(35):10648-9. Epub 2007 Aug 9. PMID:17685615

Page seeded by OCA on Mon Mar 31 04:41:34 2008

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