Ribozyme

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Line 91: Line 91:
**[[2r8s]] – RZ P4-P6 domain + antibody – mouse<BR />
**[[2r8s]] – RZ P4-P6 domain + antibody – mouse<BR />
**[[1y0q]] – RZ group I + RNA – Staphylococcus phage twort<BR />
**[[1y0q]] – RZ group I + RNA – Staphylococcus phage twort<BR />
-
**[[1x8w]] – TtRZ – ''Tetrahymena thermophilia'' group I intron<BR />
+
**[[1x8w]] – TtRZ – ''Tetrahymena thermophilia''<BR />
-
**[[1grz]] – TtRZ (mutant) <BR />
+
**[[1grz]], [[6bjx]], [[6d8l]], [[6d8m]], [[6d8n]], [[6d8o]] – TtRZ (mutant) <BR />
**[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR />
**[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR />
**[[1hr2]] - TtRZ P4-P6 domain (mutant) <BR />
**[[1hr2]] - TtRZ P4-P6 domain (mutant) <BR />
Line 99: Line 99:
**[[5j01]], [[5j02]] - RZ - ''Oceanobacillus iheyensis'' <br/>
**[[5j01]], [[5j02]] - RZ - ''Oceanobacillus iheyensis'' <br/>
-
 
+
**[[6ez0]] – yRZ - NMR<BR />
*Various ribozymes
*Various ribozymes
**[[1b36]] – RZ loop B - NMR<BR />
**[[1b36]] – RZ loop B - NMR<BR />
-
**[[2l5z]], [[1e4p]], [[2mis]] – 26-mer of VS RZ – ''Neurospora'' – NMR<BR />
+
**[[5v3i]] – VS RZ – ''Neurospora'' <BR />
 +
**[[2l5z]], [[1e4p]], [[2mis]] – 26-mer of VS RZ – NMR<BR />
**[[1yn1]], [[1yn2]], [[1tbk]], [[1tjz]], [[1hwq]] - VS RZ stem-loop V – NMR<BR />
**[[1yn1]], [[1yn2]], [[1tbk]], [[1tjz]], [[1hwq]] - VS RZ stem-loop V – NMR<BR />
**[[5v3i]] - VS RZ <BR />
**[[5v3i]] - VS RZ <BR />
Line 121: Line 122:
**[[4qjh]], [[5dun]] – twister RZ – synthetic<br />
**[[4qjh]], [[5dun]] – twister RZ – synthetic<br />
**[[4rge]], [[4rgf]] – twister RZ env22 – synthetic<br />
**[[4rge]], [[4rgf]] – twister RZ env22 – synthetic<br />
-
**[[5t5a]] – twister sister RZ – Metagenome<br />
+
**[[5t5a]], [[5y85]], [[5y87]] – twister sister RZ – Metagenome<br />
**[[5k7c]],[[5k7d]],[[5k7e]], [[5ktj]] - pistol RZ - synthetic <br/>
**[[5k7c]],[[5k7d]],[[5k7e]], [[5ktj]] - pistol RZ - synthetic <br/>
 +
**[[6gyv]] – lariat-capping RZ – ''Didymium iridis''<BR />
}}
}}

Revision as of 20:34, 14 September 2018

Hammerhead ribozyme, (PDB-ID 379d)

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3D Structures of Ribozymes

Updated on 14-September-2018

References

  1. Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
  2. Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
  3. Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551
  4. Roth A, Weinberg Z, Chen AG, Kim PB, Ames TD, Breaker RR. A widespread self-cleaving ribozyme class is revealed by bioinformatics. Nat Chem Biol. 2014 Jan;10(1):56-60. doi: 10.1038/nchembio.1386. Epub 2013 Nov, 17. PMID:24240507 doi:http://dx.doi.org/10.1038/nchembio.1386
  5. Weinberg Z, Kim PB, Chen TH, Li S, Harris KA, Lunse CE, Breaker RR. New classes of self-cleaving ribozymes revealed by comparative genomics analysis. Nat Chem Biol. 2015 Aug;11(8):606-10. doi: 10.1038/nchembio.1846. Epub 2015 Jul, 13. PMID:26167874 doi:http://dx.doi.org/10.1038/nchembio.1846

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