6mdo

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m (Protected "6mdo" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6mdo is ON HOLD
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==The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 1)==
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<StructureSection load='6mdo' size='340' side='right' caption='[[6mdo]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
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Authors: White, K.I., Zhao, M., Brunger, A.T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6mdo]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MDO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MDO FirstGlance]. <br>
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Description: The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 1)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j93|3j93]], [[3j94|3j94]], [[3j96|3j96]], [[3j97|3j97]], [[3j98|3j98]], [[3j99|3j99]]</td></tr>
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[[Category: White, K.I]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Vesicle-fusing_ATPase Vesicle-fusing ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.6 3.6.4.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mdo OCA], [http://pdbe.org/6mdo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mdo RCSB], [http://www.ebi.ac.uk/pdbsum/6mdo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mdo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NSF_CRIGR NSF_CRIGR]] Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. [[http://www.uniprot.org/uniprot/SNP25_RAT SNP25_RAT]] t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
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__TOC__
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</StructureSection>
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[[Category: Vesicle-fusing ATPase]]
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[[Category: Brunger, A T]]
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[[Category: White, K I]]
[[Category: Zhao, M]]
[[Category: Zhao, M]]
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[[Category: Brunger, A.T]]
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[[Category: Aaa]]
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[[Category: Atpase]]
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[[Category: Disassembly]]
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[[Category: Exocytosis]]
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[[Category: Hydrolase]]
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[[Category: Membrane fusion]]
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[[Category: Nsf]]
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[[Category: Snap]]
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[[Category: Snare]]
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[[Category: Synapse]]

Revision as of 19:59, 19 September 2018

The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 1)

6mdo, resolution 3.90Å

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OCA

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