Neuraminidase
From Proteopedia
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| - | *'''Neuraminidase''' | ||
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| - | **[[2ya4]], [[2w20]], [[2vvz]] – SpNANA catalytic domain – ''Streptococcus pneumoniae''<br /> | ||
| - | **[[3h71]] - SpNANA catalytic domain precursor<br /> | ||
| - | **[[4zxk]] - SpNANA carbohydrate-binding domain<br /> | ||
| - | **[[2vw0]], [[2vw1]], [[2vw2]] - SpNANB<br /> | ||
| - | **[[4xmi]], [[4xma]], [[4xjz]], [[4xj8]], [[4xio]], [[4xik]] – SpNANB (mutant)<br /> | ||
| - | **[[4yz4]], [[4yw4]] – SpNANC<br /> | ||
| - | **[[2xzi]], [[2xzj]], [[2xzk]], [[2xcy]] – NANA – ''Aspergillus fumigatus''<br /> | ||
| - | **[[2w68]] – VcNANA sialic acid binding domain – ''Vibrio cholerae''<br /> | ||
| - | **[[1w0o]], [[1kit]]– VcNANA<br /> | ||
| - | **[[1snt]], [[1so7]] – hNeu2 - human<br /> | ||
| - | **[[2f24]], [[2f26]], [[2f28]] – hNeu2 (mutant) <br /> | ||
| - | **[[1eur]] - MvNANA residues 43-407 – ''Micromonospora viridifaciens''<br /> | ||
| - | **[[1euu]] - MvNANA residues 47-647<br /> | ||
| - | **[[1wcq]], [[1w8n]], [[1w8o]], [[2hu0]], [[2hu4]] – MvNANA residues 47-647 (mutant) <br /> | ||
| - | **[[3sil]] – StNANA (mutant) – ''Salmonella typhimurium''<br /> | ||
| - | **[[4bbw]], [[5muk]] – BtNAN – ''Bacterioides thetaiotaomicron''<br /> | ||
| - | **[[5tsp]] - NANI + CHES – ''Clostridium perfringens''<br /> | ||
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| - | *Complexes of Neuraminidase | ||
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| - | **[[3h72]] - SpNANA catalytic domain precursor + sialic derivative<br /> | ||
| - | **[[3h73]] - SpNANA catalytic domain precursor + sialic acid analog<br /> | ||
| - | **[[2ya5]] - SpNANA catalytic domain + sialic acid<br /> | ||
| - | **[[2ya7]], [[2ya8]], [[5kky]], [[5f9t]] - SpNANA catalytic domain + inhibitor<br /> | ||
| - | **[[2ya6]] - SpNANA catalytic domain + sialic acid analog<br /> | ||
| - | **[[2jkb]] - SpNANB residues 30-697 + sialic acid analog<br /> | ||
| - | **[[4c1w]] - SpNANB residues 52-236 + sialic acid derivative<br /> | ||
| - | **[[4foq]], [[4fov]], [[4fow]], [[4foy]], [[4fp2]], [[4fp3]], [[4fpc]], [[4fpe]], [[4fpf]], [[4fpg]], [[4fph]], [[4fpj]], [[4fpk]], [[4fpl]], [[4fpo]], [[4fpy]], [[4fq4]] – SpNANB + inhibitor<br /> | ||
| - | **[[4xyx]] – SpNANB + drug<br /> | ||
| - | **[[4yw2]] – SpNANB residues 83-740 + sialic acid<br /> | ||
| - | **[[4xog]], [[4xjw]], [[4xj9]], [[4xil]], [[4xe9]] – SpNANB (mutant) + drug<br /> | ||
| - | **[[4xju]], [[4xja]], [[4xhx]], [[4xhb]] – SpNANB (mutant) + inhibitor<br /> | ||
| - | **[[4yz2]], [[4yw3]], [[4wy2]], [[4wy1]] – SpNANC + inhibitor<br /> | ||
| - | **[[4yw1]] – SpNANC residues 83-740 + sialic acid + neuraminic acid derivative <br /> | ||
| - | **[[4yz3]], [[4yw5]] – SpNANC + drug<br /> | ||
| - | **[[6eku]], [[6eks]] – VcNANC + drug<br /> | ||
| - | **[[1w0p]] – VcNANA + sialic derivative<br /> | ||
| - | **[[2f0z]], [[2f10]], [[2f11]], [[2f12]], [[2f13]] – hNeu2 + inhibitor<br /> | ||
| - | **[[2f25]], [[2f27]], [[2f29]], [[4nc5]], [[4ncs]] - hNeu2 (mutant) + sialic acid analog<br /> | ||
| - | **[[1vcu]] - hNeu2 + sialic acid analog<br /> | ||
| - | **[[1eus]] - MvNANA residues 43-407 + neuraminic acid derivative<br /> | ||
| - | **[[2bzd]] - MvNANA residues 47-647 (mutant) + galactose<br /> | ||
| - | **[[1eut]] - MvNANA residues 47-647 + galactose<br /> | ||
| - | **[[5mul]] – BtNAN + glucuronic acid<br /> | ||
| - | **[[2ber]] - MvNANA residues 47-647 (mutant) + sialic derivative<br /> | ||
| - | **[[1dil]], [[1dim]] – StNANA + inhibitor<br /> | ||
| - | **[[2sim]], [[2sil]] - StNANA + neuraminic acid derivative<br /> | ||
*'''Influenza virus neuraminidase''' | *'''Influenza virus neuraminidase''' | ||
Revision as of 21:35, 19 September 2018
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3D structures of Neuraminidase
Updated on 19-September-2018
References
- ↑ Matrosovich MN, Matrosovich TY, Gray T, Roberts NA, Klenk HD. Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium. J Virol. 2004 Nov;78(22):12665-7. PMID:15507653 doi:http://dx.doi.org/10.1128/JVI.78.22.12665-12667.2004
- ↑ Rutishauser U, Watanabe M, Silver J, Troy FA, Vimr ER. Specific alteration of NCAM-mediated cell adhesion by an endoneuraminidase. J Cell Biol. 1985 Nov;101(5 Pt 1):1842-9. PMID:4055897
- ↑ Colli W. Trans-sialidase: a unique enzyme activity discovered in the protozoan Trypanosoma cruzi. FASEB J. 1993 Oct;7(13):1257-64. PMID:8405811
- ↑ Sylte MJ, Suarez DL. Influenza neuraminidase as a vaccine antigen. Curr Top Microbiol Immunol. 2009;333:227-41. doi: 10.1007/978-3-540-92165-3_12. PMID:19768409 doi:http://dx.doi.org/10.1007/978-3-540-92165-3_12
- ↑ Schenkman S, Eichinger D, Pereira ME, Nussenzweig V. Structural and functional properties of Trypanosoma trans-sialidase. Annu Rev Microbiol. 1994;48:499-523. PMID:7826016 doi:http://dx.doi.org/10.1146/annurev.mi.48.100194.002435
- ↑ Russell RJ, Haire LF, Stevens DJ, Collins PJ, Lin YP, Blackburn GM, Hay AJ, Gamblin SJ, Skehel JJ. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature. 2006 Sep 7;443(7107):45-9. Epub 2006 Aug 16. PMID:16915235 doi:http://dx.doi.org/10.1038/nature05114
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