This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Symporter

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 34: Line 34:
**[[4tpg]], [[4tpj]] – SoSymp + tripeptide<BR />
**[[4tpg]], [[4tpj]] – SoSymp + tripeptide<BR />
-
*Sodium/bile acid symporter
+
*Bile acid/Na+ symporter
**[[4n7w]] – YfSymp – ''Yersinia frederiksenii''<BR />
**[[4n7w]] – YfSymp – ''Yersinia frederiksenii''<BR />
Line 51: Line 51:
**[[1pv7]], [[4oaa]] – EcSymp (mutant) + thiodigalactoside<BR />
**[[1pv7]], [[4oaa]] – EcSymp (mutant) + thiodigalactoside<BR />
-
*Sodium/glucose symporter
+
*Glucose/Na+ symporter
**[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR />
**[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR />
Line 57: Line 57:
**[[4m64]] – Symp (mutant) - ''Salmonella typhimurium''<BR />
**[[4m64]] – Symp (mutant) - ''Salmonella typhimurium''<BR />
-
*Sodium/citrate symporter
+
*Citrate/Na+ symporter
-
**[[5a1s]] – Symp + citrate – ''Salmonella enterica''<BR />
+
**[[5a1s]] – Symp + citrate + Na – ''Salmonella enterica''<BR />
-
**[[5x9r]], [[5xas]], [[5xat]] – KpSymp + citrate – ''Klebsiella pneumoniae''<BR />
+
**[[5x9r]], [[5xas]], [[5xat]] – KpSymp + citrate + Na – ''Klebsiella pneumoniae''<BR />
**[[4bpq]], [[5xar]] – KpSymp <BR />
**[[4bpq]], [[5xar]] – KpSymp <BR />
-
*Sodium/neurotransmitter symporter LeuT
+
*Neurotransmitter/leucine symporter LeuT
-
**[[3qs4]], [[3qs5]], [[3qs6]] – AaSymp (mutant) + tryptophan – ''Aquifex aeolicus''<BR />
+
**[[5jaf]], [[5jae]] – AaSymp - ''Aquifex aeolicus''<BR />
-
**[[3f4i]] – AaSymp + Na <BR />
+
**[[5jag]] – AaSymp (mutant) <BR />
 +
**[[3gjd]] – AaSymp + Na <BR />
**[[3f48]] – AaSymp + alaine + Na<BR />
**[[3f48]] – AaSymp + alaine + Na<BR />
 +
**[[3tu0]] – AaSymp (mutant) + alanine + Na <BR />
**[[3f4j]] – AaSymp + glycine + Na<BR />
**[[3f4j]] – AaSymp + glycine + Na<BR />
-
**[[2a65]] – AaSymp + leucine <BR />
+
**[[2a65]], [[3f3e]], [[3usg]], [[3usi]], [[3usj]], [[3usk]] – AaSymp + leucine + Na<BR />
-
**[[2qb4]] – AaSymp + leucine + desipramine<BR />
+
**[[3mpn]], [[3mpq]], [[3gjc]], [[4hmk]], [[4hod]], [[4fxz]] – AaSymp (mutant) + leucine + Na<BR />
-
**[[2qei]] – AaSymp + alaine + clomipramine<BR />
+
**[[3f3a]] – AaSymp + tryptophan + Na <BR />
 +
**[[3qs4]], [[3qs5]], [[3qs6]] – AaSymp (mutant) + tryptophan + Na <BR />
 +
**[[3f3c]] – AaSymp + phenylalanine + Na <BR />
 +
**[[3f3d]], [[3f4i]], [[3usl]], [[3usm]], [[3uso]] – AaSymp + methionine derivative + Na <BR />
 +
**[[4fy0]] – AaSymp (mutant) + methionine + Na <BR />
 +
**[[2qei]] – AaSymp + alaine + clomipramine + Na<BR />
**[[3gwu]] – AaSymp + sertraline + Na<BR />
**[[3gwu]] – AaSymp + sertraline + Na<BR />
-
**[[3gwv]], [[3gww]] – AaSymp + fluoxetine + Na<BR />
+
**[[3gwv]], [[3gww]], [[2qb4]], [[2q6h]], [[2q72]], [[2qju]] – AaSymp + drug + Na<BR />
 +
**[[4mm4]] – AaSymp (mutant) + drug + Na<BR />
 +
**[[3usp]] – AaSymp + glucoside derivative + Na <BR />
 +
**[[3tt1]], [[3tt3]] – AaSymp (mutant) + antibody + Na <BR />
-
*Divalent ion/sodium symporter
+
*Divalent ion/Na+ symporter
**[[5ul7]], [[5ul9]], [[5uld]], [[5ule]], [[4f35]] – Symp + Na – ''Vibrio cholerae''<BR />
**[[5ul7]], [[5ul9]], [[5uld]], [[5ule]], [[4f35]] – Symp + Na – ''Vibrio cholerae''<BR />

Revision as of 17:21, 24 September 2018

Dipeptide:H+ symporter (green) complex with dipeptide (cyan), lipid and phosphate (PDB code 4d2c)

Drag the structure with the mouse to rotate

3D Structures of symporter

Updated on 24-September-2018

References

  1. ↑ Dohan O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, Ginter CS, Carrasco N. The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocr Rev. 2003 Feb;24(1):48-77. PMID:12588808 doi:http://dx.doi.org/10.1210/er.2001-0029
  2. ↑ Pohlenz J, Refetoff S. Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism. Biochimie. 1999 May;81(5):469-76. PMID:10403177
  3. ↑ Lyons JA, Parker JL, Solcan N, Brinth A, Li D, Shah ST, Caffrey M, Newstead S. Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters. EMBO Rep. 2014 Jun 10. pii: e201338403. PMID:24916388 doi:http://dx.doi.org/10.15252/embr.201338403

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Symporter"
Personal tools