Symporter
From Proteopedia
(Difference between revisions)
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**[[4tpg]], [[4tpj]] – SoSymp + tripeptide<BR /> | **[[4tpg]], [[4tpj]] – SoSymp + tripeptide<BR /> | ||
| - | * | + | *Bile acid/Na+ symporter |
**[[4n7w]] – YfSymp – ''Yersinia frederiksenii''<BR /> | **[[4n7w]] – YfSymp – ''Yersinia frederiksenii''<BR /> | ||
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**[[1pv7]], [[4oaa]] – EcSymp (mutant) + thiodigalactoside<BR /> | **[[1pv7]], [[4oaa]] – EcSymp (mutant) + thiodigalactoside<BR /> | ||
| - | * | + | *Glucose/Na+ symporter |
**[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR /> | **[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR /> | ||
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**[[4m64]] – Symp (mutant) - ''Salmonella typhimurium''<BR /> | **[[4m64]] – Symp (mutant) - ''Salmonella typhimurium''<BR /> | ||
| - | * | + | *Citrate/Na+ symporter |
| - | **[[5a1s]] – Symp + citrate – ''Salmonella enterica''<BR /> | + | **[[5a1s]] – Symp + citrate + Na – ''Salmonella enterica''<BR /> |
| - | **[[5x9r]], [[5xas]], [[5xat]] – KpSymp + citrate – ''Klebsiella pneumoniae''<BR /> | + | **[[5x9r]], [[5xas]], [[5xat]] – KpSymp + citrate + Na – ''Klebsiella pneumoniae''<BR /> |
**[[4bpq]], [[5xar]] – KpSymp <BR /> | **[[4bpq]], [[5xar]] – KpSymp <BR /> | ||
| - | * | + | *Neurotransmitter/leucine symporter LeuT |
| - | **[[ | + | **[[5jaf]], [[5jae]] – AaSymp - ''Aquifex aeolicus''<BR /> |
| - | **[[ | + | **[[5jag]] – AaSymp (mutant) <BR /> |
| + | **[[3gjd]] – AaSymp + Na <BR /> | ||
**[[3f48]] – AaSymp + alaine + Na<BR /> | **[[3f48]] – AaSymp + alaine + Na<BR /> | ||
| + | **[[3tu0]] – AaSymp (mutant) + alanine + Na <BR /> | ||
**[[3f4j]] – AaSymp + glycine + Na<BR /> | **[[3f4j]] – AaSymp + glycine + Na<BR /> | ||
| - | **[[2a65]] – AaSymp + leucine <BR /> | + | **[[2a65]], [[3f3e]], [[3usg]], [[3usi]], [[3usj]], [[3usk]] – AaSymp + leucine + Na<BR /> |
| - | **[[ | + | **[[3mpn]], [[3mpq]], [[3gjc]], [[4hmk]], [[4hod]], [[4fxz]] – AaSymp (mutant) + leucine + Na<BR /> |
| - | **[[2qei]] – AaSymp + alaine + clomipramine<BR /> | + | **[[3f3a]] – AaSymp + tryptophan + Na <BR /> |
| + | **[[3qs4]], [[3qs5]], [[3qs6]] – AaSymp (mutant) + tryptophan + Na <BR /> | ||
| + | **[[3f3c]] – AaSymp + phenylalanine + Na <BR /> | ||
| + | **[[3f3d]], [[3f4i]], [[3usl]], [[3usm]], [[3uso]] – AaSymp + methionine derivative + Na <BR /> | ||
| + | **[[4fy0]] – AaSymp (mutant) + methionine + Na <BR /> | ||
| + | **[[2qei]] – AaSymp + alaine + clomipramine + Na<BR /> | ||
**[[3gwu]] – AaSymp + sertraline + Na<BR /> | **[[3gwu]] – AaSymp + sertraline + Na<BR /> | ||
| - | **[[3gwv]], [[3gww]] – AaSymp + | + | **[[3gwv]], [[3gww]], [[2qb4]], [[2q6h]], [[2q72]], [[2qju]] – AaSymp + drug + Na<BR /> |
| + | **[[4mm4]] – AaSymp (mutant) + drug + Na<BR /> | ||
| + | **[[3usp]] – AaSymp + glucoside derivative + Na <BR /> | ||
| + | **[[3tt1]], [[3tt3]] – AaSymp (mutant) + antibody + Na <BR /> | ||
| - | *Divalent ion/ | + | *Divalent ion/Na+ symporter |
**[[5ul7]], [[5ul9]], [[5uld]], [[5ule]], [[4f35]] – Symp + Na – ''Vibrio cholerae''<BR /> | **[[5ul7]], [[5ul9]], [[5uld]], [[5ule]], [[4f35]] – Symp + Na – ''Vibrio cholerae''<BR /> | ||
Revision as of 17:21, 24 September 2018
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3D Structures of symporter
Updated on 24-September-2018
References
- ↑ Dohan O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, Ginter CS, Carrasco N. The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocr Rev. 2003 Feb;24(1):48-77. PMID:12588808 doi:http://dx.doi.org/10.1210/er.2001-0029
- ↑ Pohlenz J, Refetoff S. Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism. Biochimie. 1999 May;81(5):469-76. PMID:10403177
- ↑ Lyons JA, Parker JL, Solcan N, Brinth A, Li D, Shah ST, Caffrey M, Newstead S. Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters. EMBO Rep. 2014 Jun 10. pii: e201338403. PMID:24916388 doi:http://dx.doi.org/10.15252/embr.201338403
