6mfs

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m (Protected "6mfs" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6mfs is ON HOLD
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==Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)==
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<StructureSection load='6mfs' size='340' side='right' caption='[[6mfs]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6mfs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MFS FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PIO:[(2R)-2-OCTANOYLOXY-3-[OXIDANYL-[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIS(OXIDANYL)-4,5-DIPHOSPHONOOXY-CYCLOHEXYL]OXY-PHOSPHORYL]OXY-PROPYL]+OCTANOATE'>PIO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mfs OCA], [http://pdbe.org/6mfs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mfs RCSB], [http://www.ebi.ac.uk/pdbsum/6mfs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mfs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
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__TOC__
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</StructureSection>
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[[Category: Chinthalapudi, K]]
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[[Category: Izard, T]]
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[[Category: Rangarajan, E S]]
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[[Category: Angiogenesis]]
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[[Category: Cell adhesion]]
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[[Category: Integrin activation]]
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[[Category: Phosphoinositide]]
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[[Category: Phospholipid]]
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[[Category: Talin activation]]

Revision as of 08:23, 26 September 2018

Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)

6mfs, resolution 2.85Å

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