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2bkk
From Proteopedia
(Difference between revisions)
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| - | ==Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the | + | ==Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a== |
<StructureSection load='2bkk' size='340' side='right' caption='[[2bkk]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='2bkk' size='340' side='right' caption='[[2bkk]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2bkk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BKK FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2bkk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BKK FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k1a|1k1a]], [[1k1b|1k1b]], [[1mj0|1mj0]], [[1n0q|1n0q]], [[1n0r|1n0r]], [[1j7i|1j7i]], [[1j7l|1j7l]], [[1j7u|1j7u]], [[1l8t|1l8t]], [[1l8u|1l8u]], [[2bkg|2bkg]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k1a|1k1a]], [[1k1b|1k1b]], [[1mj0|1mj0]], [[1n0q|1n0q]], [[1n0r|1n0r]], [[1j7i|1j7i]], [[1j7l|1j7l]], [[1j7u|1j7u]], [[1l8t|1l8t]], [[1l8u|1l8u]], [[2bkg|2bkg]]</td></tr> | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/2bkk_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/2bkk_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 37: | Line 37: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]] | ||
[[Category: Kanamycin kinase]] | [[Category: Kanamycin kinase]] | ||
| + | [[Category: Synthetic construct sequences]] | ||
[[Category: Amstutz, P]] | [[Category: Amstutz, P]] | ||
[[Category: Binz, H K]] | [[Category: Binz, H K]] | ||
| Line 57: | Line 59: | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Kinase inhibition]] | [[Category: Kinase inhibition]] | ||
| + | [[Category: Plasmid]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase-designed protein complex]] | [[Category: Transferase-designed protein complex]] | ||
[[Category: Transferase-peptide complex]] | [[Category: Transferase-peptide complex]] | ||
[[Category: Transferase/peptide]] | [[Category: Transferase/peptide]] | ||
Revision as of 08:52, 26 September 2018
Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a
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Categories: Enterococcus proteiformis thiercelin and jouhaud 1903 | Kanamycin kinase | Synthetic construct sequences | Amstutz, P | Binz, H K | Briand, C | Capitani, G | Forrer, P | Grutter, M G | Kohl, A | Parizek, P | Pluckthun, A | Ankyrin repeat | Antibiotic resistance | Atp-binding | Co-crystallization | Designed repeat protein | Drug design | Enzyme inhibition | Inhibitor design | Kinase | Kinase inhibition | Plasmid | Transferase | Transferase-designed protein complex | Transferase-peptide complex | Transferase/peptide
