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2w5z
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==Ternary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and histone peptide.== | ||
<StructureSection load='2w5z' size='340' side='right' caption='[[2w5z]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2w5z' size='340' side='right' caption='[[2w5z]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2agh|2agh]], [[2j2s|2j2s]], [[2w5y|2w5y]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2agh|2agh]], [[2j2s|2j2s]], [[2w5y|2w5y]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5z OCA], [http://pdbe.org/2w5z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w5z RCSB], [http://www.ebi.ac.uk/pdbsum/2w5z PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5z OCA], [http://pdbe.org/2w5z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w5z RCSB], [http://www.ebi.ac.uk/pdbsum/2w5z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5z ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5z_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5z_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 42: | Line 43: | ||
[[Category: Wilson, J R]] | [[Category: Wilson, J R]] | ||
[[Category: Wong, P S]] | [[Category: Wong, P S]] | ||
| + | [[Category: Alternative splicing]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Bromodomain]] | [[Category: Bromodomain]] | ||
[[Category: Chromatin regulator]] | [[Category: Chromatin regulator]] | ||
| + | [[Category: Chromosomal rearrangement]] | ||
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
[[Category: Histone modification]] | [[Category: Histone modification]] | ||
| Line 54: | Line 57: | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Protein lysine methyltransferase]] | [[Category: Protein lysine methyltransferase]] | ||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
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[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| + | [[Category: Ubl conjugation]] | ||
| + | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 09:21, 26 September 2018
Ternary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and histone peptide.
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Categories: Histone-lysine N-methyltransferase | Human | Odho, Z | Roe, S M | Southall, S M | Wilson, J R | Wong, P S | Alternative splicing | Apoptosis | Bromodomain | Chromatin regulator | Chromosomal rearrangement | Dna-binding | Histone modification | Kmt2a | Metal-binding | Methyltransferase | Mixed lineage leukaemia | Mll1 | Nucleus | Phosphoprotein | Polymorphism | Protein lysine methyltransferase | Proto-oncogene | S-adenosyl-l-methionine | Set domain | Transcription | Transcription regulation | Transferase | Ubl conjugation | Zinc | Zinc-finger
