2w5z

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==TERNARY COMPLEX OF THE MIXED LINEAGE LEUKAEMIA (MLL1) SET DOMAIN WITH THE COFACTOR PRODUCT S-ADENOSYLHOMOCYSTEINE AND HISTONE PEPTIDE.==
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==Ternary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and histone peptide.==
<StructureSection load='2w5z' size='340' side='right' caption='[[2w5z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2w5z' size='340' side='right' caption='[[2w5z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2agh|2agh]], [[2j2s|2j2s]], [[2w5y|2w5y]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2agh|2agh]], [[2j2s|2j2s]], [[2w5y|2w5y]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5z OCA], [http://pdbe.org/2w5z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w5z RCSB], [http://www.ebi.ac.uk/pdbsum/2w5z PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5z OCA], [http://pdbe.org/2w5z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w5z RCSB], [http://www.ebi.ac.uk/pdbsum/2w5z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5z ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5z_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5z_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Wilson, J R]]
[[Category: Wilson, J R]]
[[Category: Wong, P S]]
[[Category: Wong, P S]]
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[[Category: Alternative splicing]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Bromodomain]]
[[Category: Bromodomain]]
[[Category: Chromatin regulator]]
[[Category: Chromatin regulator]]
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[[Category: Chromosomal rearrangement]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]
[[Category: Histone modification]]
[[Category: Histone modification]]
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[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
[[Category: Protein lysine methyltransferase]]
[[Category: Protein lysine methyltransferase]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
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[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Ubl conjugation]]
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[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 09:21, 26 September 2018

Ternary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and histone peptide.

2w5z, resolution 2.20Å

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