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==Crystal structure of HGFA in complex with the allosteric non- inhibitory antibody Fab40.deltaTrp==
==Crystal structure of HGFA in complex with the allosteric non- inhibitory antibody Fab40.deltaTrp==
<StructureSection load='2wub' size='340' side='right' caption='[[2wub]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='2wub' size='340' side='right' caption='[[2wub]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ybw|1ybw]], [[1yc0|1yc0]], [[2wuc|2wuc]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ybw|1ybw]], [[1yc0|1yc0]], [[2wuc|2wuc]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wub OCA], [http://pdbe.org/2wub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wub RCSB], [http://www.ebi.ac.uk/pdbsum/2wub PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wub OCA], [http://pdbe.org/2wub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wub RCSB], [http://www.ebi.ac.uk/pdbsum/2wub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wub ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/2wub_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/2wub_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
*[[Hepatocyte growth factor activator|Hepatocyte growth factor activator]]
*[[Hepatocyte growth factor activator|Hepatocyte growth factor activator]]
== References ==
== References ==
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[[Category: Hydrolase-immune system complex]]
[[Category: Hydrolase-immune system complex]]
[[Category: Kringle]]
[[Category: Kringle]]
 +
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 09:33, 26 September 2018

Crystal structure of HGFA in complex with the allosteric non- inhibitory antibody Fab40.deltaTrp

2wub, resolution 2.90Å

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