Tumor necrosis factor ligand superfamily

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== Function ==
== Function ==
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Tumor necrosis factor ligand superfamily (TNFLS) is a family of TNF-like ligands. These cytokines cause wide-ranging long-term cellular activities in cells such as differentiation, proliferation or death<ref>PMID:10891884</ref>, <ref>PMID:8905447</ref>. The TNFLS are ligands for the TNF receptors.
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'''Tumor necrosis factor ligand superfamily''' (TNFLS) is a family of TNF-like ligands. These cytokines cause wide-ranging long-term cellular activities in cells such as differentiation, proliferation or death<ref>PMID:10891884</ref>, <ref>PMID:8905447</ref>. The TNFLS are ligands for the TNF receptors.
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Revision as of 18:27, 26 September 2018

Tumor necrosis factor ligand superfamily member 10 (grey, green, pink) complex with TNF receptor TRAIL (wheat, magenta, cyan), Zn+2 (grey) and Cl- (green) ions (PDB code 5cir)

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3D structures of tumor necrosis factor ligand superfamily

Updated on 26-September-2018

References

  1. ↑ Idriss HT, Naismith JH. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech. 2000 Aug 1;50(3):184-95. PMID:10891884 doi:<184::AID-JEMT2>3.0.CO;2-H http://dx.doi.org/10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H
  2. ↑ Gruss HJ. Molecular, structural, and biological characteristics of the tumor necrosis factor ligand superfamily. Int J Clin Lab Res. 1996;26(3):143-59. PMID:8905447

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Michal Harel

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