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Ubiquitin

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Line 20: Line 20:
**[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]] – hUBB – NMR - human<br />
**[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]] – hUBB – NMR - human<br />
-
**[[2ojr]], [[2nr2]], [[2fcq]], [[1ubi]], [[1ubq]], [[1xqq]], [[3ons]], [[4wzp]], [[5k9p]], [[4zqs]], [[5dk8]], [[4xof]], [[4xok]], [[4xol]], [[4zpz]] - hUBB<br />
+
**[[2ojr]], [[2nr2]], [[2fcq]], [[1ubi]], [[1ubq]], [[1xqq]], [[3ons]], [[4wzp]], [[5k9p]], [[4zqs]], [[5dk8]], [[4xof]], [[4xok]], [[4xol]], [[4zpz]] - hUBB<br />
**[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]] - hUBB (mutant)<br />
**[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]] - hUBB (mutant)<br />
**[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]] - hUBB (mutant) - NMR<br />
**[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]] - hUBB (mutant) - NMR<br />
Line 27: Line 27:
**[[1e0q]] - hUBB N-terminal (mutant) – NMR<br />
**[[1e0q]] - hUBB N-terminal (mutant) – NMR<br />
**[[3q3f]] – hUBB/ribonuclease<br />
**[[3q3f]] – hUBB/ribonuclease<br />
-
**[[4zpz]] – hPolyUBB-B (mutant)<br />
+
**[[2k39]] – fUBB – frog – NMR<br />
-
**[[5af4]], [[4xyz]] – hPolyUBB-C <br />
+
-
**[[5af5]] – hPolyUBB-C (mutant)<br />
+
-
**[[2k39]] – UBB – ''Xenopus laevis'' – NMR<br />
+
**[[2jwz]], [[1zw7]] – yUBB (mutant) – yeast<br />
**[[2jwz]], [[1zw7]] – yUBB (mutant) – yeast<br />
**[[1cmx]] – yUBB (modified)<br />
**[[1cmx]] – yUBB (modified)<br />
Line 44: Line 41:
**[[2xk5]], [[3nob]], [[2xew]], [[3h7p]], [[3h7s]], [[2w9n]], [[2jf5]], [[3ns8]], [[3aul]], [[3axc]], [[5gob]], [[5goc]], [[5god]], [[5gog]], [[5goh]], [[5goi]], [[5goj]], [[5j8p]] – hDiUBB<br />
**[[2xk5]], [[3nob]], [[2xew]], [[3h7p]], [[3h7s]], [[2w9n]], [[2jf5]], [[3ns8]], [[3aul]], [[3axc]], [[5gob]], [[5goc]], [[5god]], [[5gog]], [[5goh]], [[5goi]], [[5goj]], [[5j8p]] – hDiUBB<br />
**[[2mbo]], [[2mbq]] – hDiUBB – NMR<br />
**[[2mbo]], [[2mbq]] – hDiUBB – NMR<br />
-
**[[3m3j]], [[1aar]], [[3aui]] – bDiUBB <br />
 
**[[2bgf]] – hDiUBB – chemical relaxation<br />
**[[2bgf]] – hDiUBB – chemical relaxation<br />
-
**[[4s22]] – bDiUBB <br />
+
**[[3m3j]], [[1aar]], [[3aui]], [[4s22]] – bDiUBB <br />
* Ubiquitin dimer bound to protein
* Ubiquitin dimer bound to protein
Line 52: Line 48:
**[[3a9j]], [[3a9k]], [[2wwz]], [[2wx0]], [[2wx1]] – hDiUBB+mitogen-activated protein kinase<br />
**[[3a9j]], [[3a9k]], [[2wwz]], [[2wx0]], [[2wx1]] – hDiUBB+mitogen-activated protein kinase<br />
**[[3jsv]], [[2zvn]], [[2zvo]] – hDiUBB+NF-κ-b essential modulator<br />
**[[3jsv]], [[2zvn]], [[2zvo]] – hDiUBB+NF-κ-b essential modulator<br />
-
**[[2kde]], [[2kdf]] – DiUBB+26S proteasome non-ATPase regulatory subunit – NMR<br />
 
-
**[[3a1q]] – mDiUBB+UBB interaction motif-containing protein <br />
 
**[[3dvg]], [[3dvn]] – hDiUBB+IGG1 fab light&heavy chains<br />
**[[3dvg]], [[3dvn]] – hDiUBB+IGG1 fab light&heavy chains<br />
-
**[[2znv]] – mDiUBB+hAMSH-like protease<br />[[3ptf]] – hDiUBB + UBB conjugating enzyme E2<br />
+
**[[3b08]], [[3b0a]] – hDiUBC + HOIL-1<br />
-
**[[3b08]], [[3b0a]] – hDiUBB + HOIL-1<br />
+
**[[3u30]] – hDiUBB + antibody<br />
**[[3u30]] – hDiUBB + antibody<br />
**[[4hxd]] – hDiUBB + RNA polymerase <br />
**[[4hxd]] – hDiUBB + RNA polymerase <br />
Line 69: Line 62:
**[[3wwq]] – hDiUBB + FAAP20 peptide <br />
**[[3wwq]] – hDiUBB + FAAP20 peptide <br />
**[[5ohp]], [[5ohn]], [[5ohk]] – hDiUBB + USP30<br />
**[[5ohp]], [[5ohn]], [[5ohk]] – hDiUBB + USP30<br />
 +
**[[2kde]], [[2kdf]] – fDiUBB+26S proteasome non-ATPase regulatory subunit - NMR<br />
 +
**[[3a1q]] – mDiUBB+UBB interaction motif-containing protein <br />
 +
**[[2znv]] – mDiUBB+hAMSH-like protease<br />[[3ptf]] – hDiUBB + UBB conjugating enzyme E2<br />
* Ubiquitin trimer
* Ubiquitin trimer
Line 75: Line 71:
**[[3zlz]], [[5o44]] – hTriUBB (mutant) <br />
**[[3zlz]], [[5o44]] – hTriUBB (mutant) <br />
**[[4boz]] – hTriUBB + UBB thiolesterase <br />
**[[4boz]] – hTriUBB + UBB thiolesterase <br />
-
**[[3vuw]], [[3vux]], [[3vuy]] – hTriUBB + TNF α-induced proitein <br />
+
**[[3vuw]], [[3vux]] – hTriUBB + TNF α-induced proitein <br />
* Ubiquitin tetramer
* Ubiquitin tetramer
Line 84: Line 80:
**[[3zni]] – hTetraUBB + E3 UBB protein ligase + tyrosine protein kinase + UBB conjugating enzyme E2<br />
**[[3zni]] – hTetraUBB + E3 UBB protein ligase + tyrosine protein kinase + UBB conjugating enzyme E2<br />
**[[5b83]] – hTetraUBB + optineurin<br />
**[[5b83]] – hTetraUBB + optineurin<br />
 +
**[[3vuy]] – hTetraUBB + TNF α-induced proitein <br />
* Polyubiquitin-B
* Polyubiquitin-B
Line 139: Line 136:
**[[2l0t]] – hUBB+signal transducing adapter molecule 2<br />
**[[2l0t]] – hUBB+signal transducing adapter molecule 2<br />
**[[3o65]] – hUBB+ataxin-3-like protein josephin domain<br />
**[[3o65]] – hUBB+ataxin-3-like protein josephin domain<br />
-
**[[3oj3]] – hUBB+tumor necrosis factor -induced protein 3<br />
+
**[[3oj3]] – hUBB+tumor necrosis factor α-induced protein 3<br />
-
**[[3phd]] – hPolyUBB+histone deacetylase 6<br />
+
-
**[[3znh]] – hPolyUBB-B + UBB thioesterase<br />
+
-
**[[4uf6]] – hPolyUBB-B + UCH-L5 + NF-κ-b-related protein<br />
+
-
**[[3znz]] – hPolyUBB-C + otulin<br />
+
-
**[[4jqw]] – hPolyUBB-C + NOD1 CARD<br />
+
-
**[[4k1r]] – hPolyUBB-C + SST2<br />
+
**[[3prm]], [[3prp]] – hUBB+protein L<br />
**[[3prm]], [[3prp]] – hUBB+protein L<br />
**[[3pt2]] – hUBB+RNA polymerase OTU domain<br />
**[[3pt2]] – hUBB+RNA polymerase OTU domain<br />
**[[5v5i]], [[5v5h]], [[5v5g]] - hUBB+RNA polymerase L<br />
**[[5v5i]], [[5v5h]], [[5v5g]] - hUBB+RNA polymerase L<br />
**[[2rr9]] – hUBB + Uimc1<br />
**[[2rr9]] – hUBB + Uimc1<br />
-
**[[1fxt]], [[3oj4]], [[3ugb]], [[5dfl]], [[3k9p]], [[3a33]] – hUBB + UBB conjugating enzyme E2<br />
 
-
**[[2fuh]] – hUBB + UBB conjugating enzyme E2 - NMR<br />
 
-
**[[4auq]] – hUBB + UBB conjugating enzyme E2 + livin<br />
 
**[[2g45]] – hUBB + isopeptidase T<br />
**[[2g45]] – hUBB + isopeptidase T<br />
**[[2den]] – hUBB + immunoglobulin G binding protein/ubiquitin-like protein 7 - NMR<br />
**[[2den]] – hUBB + immunoglobulin G binding protein/ubiquitin-like protein 7 - NMR<br />
-
**[[2oob]], [[2qho]] – hUBB + E3 UBB protein ligase<br />
+
**[[4xkl]] – hUBB + NDP52<br />
-
**[[2lvo]] – hUBB + E3 UBB protein ligase - NMR<br />
+
**[[4zfr]], [[4zft]] – hUBB + SST2<br />
**[[2j7q]] – hUBB + MCMV tegument protein<br />
**[[2j7q]] – hUBB + MCMV tegument protein<br />
**[[4dhj]], [[4dhz]] – hUBB (mutant) + UBB thiolesterase + UBB aldehyde <br />
**[[4dhj]], [[4dhz]] – hUBB (mutant) + UBB thiolesterase + UBB aldehyde <br />
Line 201: Line 189:
**[[1otr]] – yUBB+CUE2<br />
**[[1otr]] – yUBB+CUE2<br />
**[[2l00]] – yUBB + Zfand5<br />
**[[2l00]] – yUBB + Zfand5<br />
-
**[[4q5h]], [[4q5e]] – yUBB + UBB conjugating enzyme E2 + OspG<br />
 
**[[4nql]] – mUBB + AMSH-like protease<br />
**[[4nql]] – mUBB + AMSH-like protease<br />
Line 213: Line 200:
**[[5tr4]] – bUBB + UBB activating enzyme E1<br />
**[[5tr4]] – bUBB + UBB activating enzyme E1<br />
**[[2gmi]] – hUBB + UBB conjugating enzyme E2<br />
**[[2gmi]] – hUBB + UBB conjugating enzyme E2<br />
 +
**[[2fuh]] – hUBB + UBB conjugating enzyme E2 - NMR<br />
**[[5d0k]], [[5d0m]], [[5ulk]], [[5ulh]] – hUBB + UBB conjugating enzyme E2 + RNF165<br />
**[[5d0k]], [[5d0m]], [[5ulk]], [[5ulh]] – hUBB + UBB conjugating enzyme E2 + RNF165<br />
-
**[[4xkl]] – hUBB + NDP52<br />
+
**[[2oob]], [[2qho]] – hUBB + E3 UBB protein ligase<br />
-
**[[4zfr]], [[4zft]] – hUBB + SST2<br />
+
**[[2lvo]] – hUBB + E3 UBB protein ligase - NMR<br />
**[[5o76]] – hUBB + Zap70 peptide + E3-UBB-protein ligase CBL<br />
**[[5o76]] – hUBB + Zap70 peptide + E3-UBB-protein ligase CBL<br />
-
**[[2fuh]] – hUBB + UBB conjugating enzyme E2 - NMR<br />
 
**[[4auq]] – hUBB + UBB conjugating enzyme E2 + livin<br />
**[[4auq]] – hUBB + UBB conjugating enzyme E2 + livin<br />
**[[4q5h]], [[4q5e]] – yUBB + UBB conjugating enzyme E2 + OspG<br />
**[[4q5h]], [[4q5e]] – yUBB + UBB conjugating enzyme E2 + OspG<br />

Revision as of 18:04, 2 October 2018

Human ubiquitin (green) complex with ubiquitin-conjugating enzyme E2 (deep sky blue), 3k9p

Drag the structure with the mouse to rotate

3D Structures of Ubiquitin

Updated on 02-October-2018

References

  1. ↑ Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem. 1998;67:425-79. PMID:9759494 doi:http://dx.doi.org/10.1146/annurev.biochem.67.1.425
  2. ↑ Paul S. Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches. Bioessays. 2008 Nov;30(11-12):1172-84. doi: 10.1002/bies.20852. PMID:18937370 doi:http://dx.doi.org/10.1002/bies.20852
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