6dik
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Bothropstoxin I (BthTX-I) complexed to Chicoric acid== | |
| - | + | <StructureSection load='6dik' size='340' side='right' caption='[[6dik]], [[Resolution|resolution]] 1.93Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dik]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DIK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DIK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GKP:(2R,3R)-2,3-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}butanedioic+acid'>GKP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iq3|3iq3]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dik OCA], [http://pdbe.org/6dik PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dik RCSB], [http://www.ebi.ac.uk/pdbsum/6dik PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dik ProSAT]</span></td></tr> |
| - | [[Category: Cardoso, F | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/PA2B1_BOTJR PA2B1_BOTJR]] Snake venom phospholipase A2 homolog that lacks enzymatic activity. In vivo, induces muscle necrosis, accompanied by polymorphonuclear cell infiltration, and edema in the mouse paw. Damages artificial and myoblast membranes by a calcium-independent mechanism. Has bactericidal activity.<ref>PMID:3176051</ref> <ref>PMID:11018293</ref> <ref>PMID:11829743</ref> <ref>PMID:12079495</ref> <ref>PMID:17346668</ref> <ref>PMID:18160090</ref> <ref>PMID:17157889</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bothrops jararacussu]] | ||
| + | [[Category: Borges, R J]] | ||
| + | [[Category: Cardoso, F F]] | ||
| + | [[Category: Salvador, G H.M]] | ||
| + | [[Category: Bothropd jararacussu]] | ||
| + | [[Category: Bthtx-i]] | ||
| + | [[Category: Chicoric acid]] | ||
| + | [[Category: Cichoric acid]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Pla2]] | ||
| + | [[Category: Toxin]] | ||
Revision as of 07:47, 3 October 2018
Crystal structure of Bothropstoxin I (BthTX-I) complexed to Chicoric acid
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