6fuf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Crystal structure of the rhodopsin-mini-Go complex== |
| - | + | <StructureSection load='6fuf' size='340' side='right' caption='[[6fuf]], [[Resolution|resolution]] 3.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fuf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FUF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FUF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fuf OCA], [http://pdbe.org/6fuf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fuf RCSB], [http://www.ebi.ac.uk/pdbsum/6fuf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fuf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN]] Early infantile epileptic encephalopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref> [[http://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Carpenter, B]] | ||
| + | [[Category: Deupi, X]] | ||
| + | [[Category: Edwards, P C]] | ||
| + | [[Category: Flock, T]] | ||
| + | [[Category: Gruhl, T]] | ||
| + | [[Category: Ma, P]] | ||
| + | [[Category: Muehle, J]] | ||
| + | [[Category: Nehme, R]] | ||
| + | [[Category: Nogly, P]] | ||
| + | [[Category: Pamula, F]] | ||
| + | [[Category: Schertler, G F.X]] | ||
| + | [[Category: Standfuss, J]] | ||
| + | [[Category: Tate, C G]] | ||
| + | [[Category: Tsai, C J]] | ||
| + | [[Category: Weinert, T]] | ||
| + | [[Category: Gpcr complex rhodopsin]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 07:52, 3 October 2018
Crystal structure of the rhodopsin-mini-Go complex
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Categories: Carpenter, B | Deupi, X | Edwards, P C | Flock, T | Gruhl, T | Ma, P | Muehle, J | Nehme, R | Nogly, P | Pamula, F | Schertler, G F.X | Standfuss, J | Tate, C G | Tsai, C J | Weinert, T | Gpcr complex rhodopsin | Signaling protein
