6cj1
From Proteopedia
(Difference between revisions)
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<StructureSection load='6cj1' size='340' side='right' caption='[[6cj1]], [[Resolution|resolution]] 1.53Å' scene=''> | <StructureSection load='6cj1' size='340' side='right' caption='[[6cj1]], [[Resolution|resolution]] 1.53Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6cj1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CJ1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6cj1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CJ1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F2S:11-[(2R)-butan-2-yl]-2-({2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one'>F2S</scene>, <scene name='pdbligand=FND:11-[(2S)-butan-2-yl]-2-({2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one'>FND</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F2S:11-[(2R)-butan-2-yl]-2-({2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one'>F2S</scene>, <scene name='pdbligand=FND:11-[(2S)-butan-2-yl]-2-({2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one'>FND</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cj1 OCA], [http://pdbe.org/6cj1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cj1 RCSB], [http://www.ebi.ac.uk/pdbsum/6cj1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cj1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cj1 OCA], [http://pdbe.org/6cj1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cj1 RCSB], [http://www.ebi.ac.uk/pdbsum/6cj1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cj1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Blacklow, S C]] | [[Category: Blacklow, S C]] | ||
[[Category: Xu, X]] | [[Category: Xu, X]] | ||
Revision as of 08:43, 3 October 2018
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG071
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