Uridylate kinase
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
| - | The biological assembly of Uridylate kinase from ''Sulfolobus solfataricus'' ([[2j4k]]) is <scene name='48/487531/Cv/2'>homohexamer</scene>. The <scene name='48/487531/Cv/3'>active site of UK has high specificity to uracil</scene> and excludes purine nucleotides<ref>PMID:17297917</ref>. Water molecule shown as | + | The biological assembly of Uridylate kinase from ''Sulfolobus solfataricus'' ([[2j4k]]) is <scene name='48/487531/Cv/2'>homohexamer</scene>. The <scene name='48/487531/Cv/3'>active site of UK has high specificity to uracil</scene> and excludes purine nucleotides<ref>PMID:17297917</ref>. Water molecule shown as gold sphere. |
</StructureSection> | </StructureSection> | ||
==3D structures of uridylate kinase== | ==3D structures of uridylate kinase== | ||
Revision as of 18:04, 5 October 2018
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3D structures of uridylate kinase
Updated on 05-October-2018
References
- ↑ Yan H, Tsai MD. Nucleoside monophosphate kinases: structure, mechanism, and substrate specificity. Adv Enzymol Relat Areas Mol Biol. 1999;73:103-34, x. PMID:10218107
- ↑ Jensen KS, Johansson E, Jensen KF. Structural and enzymatic investigation of the Sulfolobus solfataricus uridylate kinase shows competitive UTP inhibition and the lack of GTP stimulation. Biochemistry. 2007 Mar 13;46(10):2745-57. Epub 2007 Feb 13. PMID:17297917 doi:10.1021/bi0618159
